2022 Global Year - Translating Pain Knowledge to Practice

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Global Year focuses on a special aspect of pain to increase awareness within the pain community and beyond. The 2022 Global Year aims to raise awareness about integrative pain care and illustrate the knowns and unknowns of this important topic via different initiatives, including a fact sheet series and several webinars.

Success Stories: Translating Insights from Genetic Analyses in Painful Small Fiber Neuropathy into Pharmacological Practice - Lacosamide
Speakers: Karin Faber, MD, PhD, Heike Rittner, MD

New Stories: Translating Findings From Nonpharmacological Interventions into Practice: Neuromodulation
Speakers: Didier Bouhassira, MD, PhD, Sulayman Dib-Hajj, PhD

The Restorative Model: Antiracism in Pain Research and Clinical Care
Speakers: Anna Hood, PhD, Janelle Letzen, PhD, Calia Morais, PhD, Joletta Belton, MSc

Translating Genome-Wide Transcriptomics Data for Understanding the Pathophysiology of Human Pain
Speakers: Luda Diatchenko, MD, PhD, Jeffrey Mogil, PhD

A Functional Subdivision Within the Somatosensory System and its Implications for Pain Research
Speakers: Qiufu Ma, PhD, Claudia Sommer, MD

New stories: Translating Pain Knowledge of Rare Diseases and Understudied Ethnic Groups: Sickle Cell Anemia
Speakers: Keesha Roach, PhD, Staja Booker, PhD, RN

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Success Stories: Translating Insights from Genetic Analyses in Painful Small Fiber Neuropathy into Pharmacological Practice - Lacosamide
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Open to view video. This webinar, hosted on 5 April 2022, was the first webinar of the IASP 2022 Global Year - Translating Pain Knowledge to Practice. The webinar focused on lacosamide, a Food and Drug Administration-approved treatment for epilepsy, and how insights from the genetic analyses of pain patients led to its investigation for use in the management of neuropathic pain. There was a presentation by: Karin Faber, MD, PhD, Maastricht University, the Netherlands Heike Rittner, MD, University Hospital of Würzburg, Germany (moderator)
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New Stories: Translating Findings from Nonpharmacological Interventions into Practice: Neuromodulation
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Open to view video. This webinar discusses neuromodulation techniques are widely and long-establishedly used in the treatment of chronic pain. The classical techniques include: transcutaneous electrical stimulation (TENS), electrical stimulation of the dorsal columns of the spinal cord, epidural stimulation of the motor cortex. More recently new non-invasive electrical (TENS) or magnetic (rTMS) cortical stimulation, vagal stimulation, or occipital stimulation have been developed. Speakers: Didier Bouhassira, MD, PhD Sulayman Dib-Hajj, PhD
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The Restorative Model: Antiracism in Pain Research and Clinical Care
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Open to view video. This webinar, hosted on 26 July 2022, is the third webinar of the IASP 2022 Global Year - Translating Pain Knowledge to Practice. The webinar is titled: ‘The Restorative Model: Antiracism in Pain Research and Clinical Care’ and is presented by: Anna Hood, PhD Janelle Letzen, PhD Calia Morais, PhD Joletta Belton, MSc This webinar will provide an opportunity to discuss the historical context and implications for applying an antiracism framework across all forms of pain research. The presenters will provide examples and reframes to illustrate how antiracism practices are a shared commitment to reach equity in pain science.
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Translating Genome-Wide Transcriptomics Data for Understanding the Pathophysiology of Human Pain
Open to view video.
Open to view video. This webinar will provide an opportunity to discuss the value of human molecular-omics data for reconstructing human pain states with subsequent mechanistic animal experiment. Dr. Luda Diatchenko, MD, PhD will be presenting new data from her program for the first 40 min, and Dr. Jefferey Mogil, PhD will moderate the discussion.
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A Functional Subdivision Within the Somatosensory System and its Implications for Pain Research
Open to view video.
Open to view video. Pain research currently faces translational crisis, with few preclinical studies translating to new pain medicines. In this talk, Dr. Ma will discuss a new anatomical and functional subdivision of the somatosensory system: one for detecting external threats and driving reflective-defensive reactions to prevent or limit injury, and the other for monitoring internal body injury that produces affective tonic pain and drives self-caring response to reduce suffering. With this circuit-level segregation, he argues that reflexive-defensive assays may not necessarily be able to detect selective loss of clinically more relevant pain, and their wide use by the pain field could contribute to poor translational success. Faculty: Qiufu Ma, PhD Claudia Sommer, MD
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New stories: Translating Pain Knowledge of Rare Diseases and Understudied Ethnic Groups: Sickle Cell Anemia
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Open to view video. This presentation focuses on omics and other tools used to understand pain in sickle cell disease. We will review how key discoveries in SCD research over the years have been translated to change how we treat the disease and the whole-person. Faculty: Keesha Roach, PhD Staja Booker, PhD, RN
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