IASP 2022 World Congress on Pain

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Recordings and slides from the IASP 2022 World Congress on Pain in Toronto

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Calcitonin Gene-Related Peptide and Pain
Calcitonin Gene-Related Peptide and Pain
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Open to download resource. This presentation will introduce CGRP and its receptors. The molecular composition and pharmacology of these receptors will be explained, together with an overview of their signaling and expression, with an emphasis on cephalic pain.
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CGRP Signaling in Non-Cephalic Pain
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Open to view video.
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CGRP Signaling in Cephalic Pain
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Open to download resource. Calcitonin gene related peptide (CGRP) is widely distributed in the human peripheral and central nervous system including pain pathways. Monoclonal antibodies against CGRP or its receptor have proved to be highly effective for the treatment of migraine. Equally important and in contrast to what could be expected from inhibiting a widely distributed peptide, the drugs are very well tolerated. In fact, the introduction of CGRP antibodies in the field of migraine has been among the largest gamechangers ever seen in the management of migraine. Data from controlled studies on treatment with CGRP antibodies in migraine as well as cluster headache, trigeminal neuralgia, posttraumatic headache, and osteoarthritis will be presented and discussed with the audience.
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Functional Biomarkers of Nociceptive Signal Processing - Back-Translation of Human Studies to Preclinical Models
Neurophysiological Biomarkers for Central Sensitization in Humans
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Functional Neuroimaging and Psychophysics as Potential Biomarkers of Chronic Pain and Predictors of Treatment Outcome
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It's Difficult to Make Predictions: Data Mining and Machine Learning in Pain Research and Management
Machine Learning: What it Can, Cannot, and Should Not Do
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Open to download resource. While the statistical models for machine learning have mostly been developed in the 20th century, with the wide availability of cheap computing and virtually endless data space, data mining and machine learning have become an accessible and mighty tool for researchers outside highly specialized groups. Beyond research, they have become a ubiquitous part of our daily life, as predictive text suggestions on our emails or face recognition to unlock our phones. This presentation will provide an overview of history, methods, and increasing usage of machine learning, from high-end research over daily life improvements to preclinical and clinical opportunities for pain research. A special focus will be set on common misconceptions, inherent bias, and the dangers of (mis)use of computational decision making.
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Extracting Useful Epidemiological Data on Pain from Public Datasets
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Open to download resource. Numerous health-related open datasets exist, many of which span decades. Examples include the Global Burden of Disease dataset, NHS England GP prescribing data, and US health population surveys such as the National Health and Nutrition Examination Survey (NHANES). While these datasets are public, they either were not designed to directly address issues related to pain, or they are heterogenous (within and between surveys) in terms of the pain-related questions that have been asked over time. Nevertheless, these are rich datasets for obtaining high-level epidemiological data on pain, its consequences, and its treatment. In this presentation the wealth of information contained in these datasets and the methods used to identify, extract and analyse such data in order to achieve novel insights into pain at national and global levels will be shown to the audience.
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What are Risk Factors for Painful Polyneuropathy? An Analysis Using Machine Learning
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Open to download resource. In this workshop we will explore the application of data analytics to such datasets across a diverse range of pain-related topics, demonstrating the flexibility and power of analytical methods to generate novel insights in both basic science and clinical research. Jan Vollert will open the workshop by giving an introduction into data mining and machine learning, setting foundation knowledge about best practices and pitfalls in a fast-evolving, hot topic. Peter Kamerman will speak on using publicly accessible datasets (e.g., global burden of disease data, NHS England prescribing data, and general health survey data from the US) to gain high-level epidemiological insights into pain burden and the management of pain. Finally, Janne Gierthmühlen will present data on predicting development of chronic pain in longitudinal studies of populations at risk, like diabetes.
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Moving Beyond the Means and Standard Deviations in Pain Research - Insights to Enhance Personalized Pain Care
Using Person-Centered Analytic Approaches as Primary Outcomes in Postoperative Pain and Recovery Research
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Open to download resource. Recovery from pain after surgery is usually studied in a cross-sectional manner. This lecture discusses how this method provides information only on the small number of individuals with continuing pain and fails to quantify the burden of pain over time since surgery in everyone. It describes how more frequent assessments of pain after surgery can be acquired and analyzed using growth curve models appropriate for person-centered forecasting and latent class analysis. The increased precision and statistical power of this approach compared to classic repeated measure ANOVA methods when examining interventions to speed recovery after surgery will also be discussed. Data from two recent interventional clinical trials which used daily assessments for 2 months after surgery to define person-centered modeled trajectory as the primary outcome measure will be contrasted with the traditional dichotomous, cross sectional outcome. Finally, challenges to gathering daily data in this research context and approaches to overcome those challenges will be presented.
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Moving Towards Person-Centered Analytic Approaches in Cancer Pain and Symptom Research and Care
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Using Trajectories of Acute Pain After Surgery to Guide Interventions in a Transitional Pain Service
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Open to download resource. The Canadian Pain Task Force (CPTF) established the prevention and management of chronic pain as a top priority for Canadians. The Transitional Pain Service (TPS) at the Toronto General Hospital was highlighted as an innovation in pain care. The service has developed over time to secure sustainable multidisciplinary interventions for the prevention and management of chronic postsurgical pain (CPSP) and persistent opioid use following surgery. A review of the known risk factors associated with the development CPSP across the life span will be discussed. Moving beyond risk factors, publications have outlined acute pain trajectories that suggest patterns of pain with a link to the development of CPSP. Within the TPS, pain intensity and opioid use in the days following surgery can guide interventions and signal patients that need increased resources upon presentation to the clinic.
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Opioids in the Perioperative Setting: Should We Be Worried?
The Role of Acute Care Prescribing in the Opioid Epidemic
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Open to download resource. Dr. Brummett will discuss how prescribing after surgery has directly impacted the opioid epidemic in the US and Canada and how the same factors that increased prescribing and morbidity is currently spreading around the world due to changes in opioid prescribing and postoperative care patterns. He will show that while increased opioid prescribing after surgery does not improve pain or satisfaction, it is associated with increased new chronic use, morbidity and cost of care.
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Opioid Related Complications in the Perioperative Setting - a Deal with the Devil?
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A Personalized Approach to Opioid Use Based on Brain Networks
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Pain in People with Intellectual and Developmental Disabilities Across the Life Span: Where Do We Go from Here?
Quantitative and Behavioral Approaches to Pain Assessment in IDD
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Pain Management in Individuals with Intellectual Disabilities
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Open to view video.
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The Use of Cognitive Behavioural Techniques for Pain Management in People with an Intellectual Disability
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Schwann Cell Renaissance in Pain: Critical Appraisal of New Knowledge on Old Cells
Schwann Cells In Patients with Painless and Painful Diabetic Peripheral Neuoropathy
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Schwann Cell Extracellular Vesicles Are Innovative Regulators Of Neuroinflammation And Pain
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Nociceptor Sensitization – News From Patients and Patient-Derived In Vitro Systems at the Neuro-C
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Translating Basic Models of Muscle Pain: A Focus on Sex Differences
Sex Specific Peripheral Mechanisms of Ischemic Myalgia
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Osteochondral Pathologies Associated with Pain in Osteoarthritis
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Sex, Gender and Pain: Past, Present and Future
Sex, Gender and Pain: Past, Present and Future
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A Translational Approach to Mechanistic-Based Pain Medicine
Pre-Clinical Identification of Pain Mechanisms and the Likelihood of Clinical Translation for Analgesic Optimisation
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Parallel Studies in Mice and Men by Using QST and Non-Evoked Pain Measures
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The Predictive Value of Mechanistic Pain Profiling, and How this Can Enrich Clinical Pain Research
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Advancing the Science and Management of Chronic Pain through its Classification in ICD-11: Perspectives from Patient and Specialized Pain Clinic Viewpoints
Chronic Pain in the ICD-11: Introduction to the New Diagnoses and Their Scientific Evidence
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Patients' Acceptance of the New Classification for Chronic Pain
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Opportunities and Challenges of the Implementation of the ICD-11 Pain Classification in the Clinical Routines of an Interdisciplinary Persistent Pain Service in New Zealand
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The Survey of Implementing the ICD-11 Chronic Pain Classification in Multidisciplinary Pain Centers of Japan
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Chemotherapy-Induced Peripheral Neuropathy: Pathophysiology and Mechanism-Based Treatment
Insights into the Contribution of Nav Channels to CIPN
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Neuronal Interaction with the Extracellular Environment in the Models of CIPN
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Macrophage-Derived Interleukin-1 is both Necessary and Sufficient for Vincristine-Induced Peripheral Neuropathy
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Improving Reproducibility and Translatability in Pre-Clinical Pain Research - Some Practical Solutions
Using Topical Findings from Psychology to Update Your Basic Statistical Toolkit
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Novel Resources to Optimise Internal Validity and Reduce Risk of Bias for Pre-Clinical Study Designs: Presenting the Outputs of the European Quality In Preclinical Data (EQIPD) Consortium
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Reproducibility in Pre-Clinical Drug Efficacy Studies: Results of an ACTTION-Funded Multi-Site Comparative Study
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Mechanisms Leading to the Female-Biased Nature of Migraine: Moving Beyond Estrogen
Hypothalamic Stress Circuits Regulate Prolactin to Promote Female-Selective Nociceptor Sensitization and Migraine-Like Pain
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Hypothalamic Stress Circuits Regulate Prolactin to Promote Female-Selective Nociceptor Sensitization and Migraine-Like Pain
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Sex and Gender-Specific Peripheral Trigeminovascular Actions of CGRP in Migraine
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Nocebo Effects in Pain: From Mechanisms to Therapeutic Treatments in Clinical Practice
Explaining the Mechanism of Nocebo Effects
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Identifying Novel Behavioral Strategies to Inhibit Nocebo Hyperalgesia
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Open to view video.
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How to Reduce Nocebo Effects in Pain
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John D. Loeser Award Lecture: The Biopsychosocial Model of Pain Is Now 40 Years Old: Time for a Reappraisal?
John D. Loeser Award Lecture: The Biopsychosocial Model of Pain Is Now 40 Years Old: Time for a Reappraisal?
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Cytokines and Pain
Cytokines and Pain
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Alpha Oscillations as a Potential Biomarker of Acute and Chronic Pain
The Alpha Activity in the Human Brain: A Conundrum with High Potentialities for Pain Research
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Peak Alpha Frequency is a Simple and Reliable Metric of Pain Sensitivity
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Peak Alpha Frequency as a Potential Biomarker of Chronic Neuropathic Pain with Some Sex Specificity
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Angiotensin Receptor Signaling as a Pain Target: Bench, Bedside and Back-Translation
Targeting Angiotensin Receptor Signaling for Neuropathic Pain: Clinical Trials and the Development Landscape
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Neuroimmune Interactions and Angiotensin Receptor Signaling in Neuropathic Pain and Beyond
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Nociplastic Pain - What Clinicians Need to Understand: Recent Insights, Presentation of New Clinical Criteria and Future Development
Clinical Criteria and Grading of Nociplastic Pain, Where Do We Stand?
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How Do We Examine and Interpret Pain Hypersensitivity Phenomena in the Context of Nociplastic Pain?
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Plexus Injury: Plasticity of the Human Dorsal Root Ganglion, Satellite Glia and Reinnervation
Plasticity of the Dorsal Root Ganglion, Clinical Characteristics, and Treatment After Plexus Injury in Patients
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Satellite Glial Cells in Sensory Nervous System Health, Injury and Disease
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Abnormal Reinnervation After Nerve Injury and its Effects on Pain
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Open to view video.
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The Amygdala as a Master Generator of Pain Plasticity - From Nociceptive Amygdala to Nociplastic Amygdala
Dual and Opposing Functions of the Central Amygdala in Pain Modulation
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Role of Amygdala Neuro-Immune Signaling in Chronic Neuroplasticity and Pain Behaviors
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The Central Amygdala in Widespread Sensitization in Rodent Models of Nociplastic Pain
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What Are Sleeping C-Fiber Nociceptors? Taking a Question from Human Physiology to Experiment
The Answer is the Cellular Function: Electrophysiology of iPS-cell Derived and Porcine Sensory Neurons
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Framing the Question: What are Sleeping Human Nociceptors? Why do Classes of C-fibers Show a Specific Response Pattern to Electrical Stimulation?
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The Answer is All in the Genes: RNASeq of Human Sensory Neurons
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The Answer is the Synthesis of Both: PatchSeq Takes our Knowledge in Neuron Classification to the Next Level
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What's New in Combination Pharmacotherapy for Neuropathic Pain? From Bench to Bedside
Clinical Research and Evidence Surrounding Combination Pharmacotherapy for Neuropathic Pain
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Combination Pharmacotherapy in Real-World Management of Neuropathic Pain
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Preclinical Approaches to the Understanding and Development of Analgesic Combination Therapy
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The Genesis of the Unequal Burden of Pain: A Selective Review Examining Social Inequities and Unheard Voices
The Genesis of the Unequal Burden of Pain: A Selective Review Examining Social Inequities and Unheard Voices
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Mechanisms and Manifestations in Musculoskeletal Pain - From Experimental to Clinical Pain Settings
Mechanisms and Manifestations in Musculoskeletal Pain - from Experimental to Clinical Pain Settings
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Clinical Aspects of Tapering Opioids for Chronic Non-Cancer Pain. Presentation of Research Results from UK, US and Canada
What Physicians Don't Know That They Don't Know About Opioid Prescribing
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Improving the Wellbeing of Opioid Treated Chronic Pain (I-WOTCH): Results of a UK Randomised Controlled Trial
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STRIPE Trial: Pain Self-Management Training and Medication Support for Opioid Taper
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Contribution of Itch, Inflammation, and the Microbiota to Colorectal Nociception; Opportunities for Therapeutic Intervention?
Contribution of the Microbiota to Colorectal Nociception
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Contribution of Inflammation to Colorectal Nociception
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Contribution of Itch Signalling Pathways to Colorectal Nociception
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Generalization in the Context of Pain: Both Good and Bad?
Overgeneralization of Pain-Related Fear and Avoidance
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The Bright and Dark Side of Generalization in Pain
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Neural Mechanisms Underlying Overgeneralization of Valence-Based Learning
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Mechanisms of Susceptibility/Resistance to Chronic Pain Development
Factors of Susceptibility/Resistance to Chronic Pain in a Peripheral Neuropathy Model
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Psychobiological and Learning-Related Mechanisms Involved in the Development of Chronic Pain
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Lifecourse Approaches and Risk of Developing Chronic Pain Trajectories
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Motor Control Adaptions in Low Back Pain: Do they Matter?
Reconnecting the Brain with the Rest of the Body: Brain and Biomechanical Mechanisms Associated with Persistent Low Back Pain
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Motor Adaptation in the Transition from Acute to Chronic Pain
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Paradoxical Findings on Motor Adaptations in LBP May be Explained by a Single Mechanism
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News from the Brainstem: Functional Plasticity in Noradrenergic Nuclei Upon Stress and Injury
Reciprocity between Brainstem Noradrenergic Nuclei in Health and Disease
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Affective and Sensory Disorders in Pain Processing: Higher Brain and Brainstem Circuits that Regulate Pain Inhibition and Facilitation
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Non-Neuronal Cells in Chronic Pain: From Single-Cell Analysis to Translational Targets
Spinal Cord Microglial Heterogeneity as a Target for Chronic Pain
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Role of Satellite Glial Cells and Metalloproteinase Signaling in Pain
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Meningeal Immune Cells as Triggers for Neuropathic Pain
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Offset Analgesia: At the Crossroads of Pain Modulation and Chronicity
An Overview of Offset Analgesia: Mechanisms and Functional Significance
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\The Relevance of Offset Analgesia in Clinical Practice
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Offset Analgesia Provides Diagnostic Modality and Mechanistic Insight into Chronic Pain
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Pain Assessment in Dementia: Guidelines, Gaps, Automation and Knowledge Mobilization
The State of the Art of Using Standardized Tools for Pain Assessment in Dementia
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Automatic Pain Recognition Systems in Dementia: Are We There Yet?
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Transition to Chronic Pain: Risk Factors and Evidence for Prevention and Mitigation Strategies
Risk Factors and Clinical Predictors of Chronic Pain After Surgery and Acute Injury
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Clinical Research and Evidence for Non-Pharmacological Interventions to Prevent Transition to Chronic Pain
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Ronald Melzack Award Lecture: Mosaic of "Pain Genes" and Biological Pathways Contributing to Human Pai
Ronald Melzack Award Lecture: Mosaic of "Pain Genes" and Biological Pathways Contributing to Human Pain
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Neuroimaging of Pain and Affect: Pathways, Biomarkers, and Interventions
Neuroimaging of Pain and Affect: Pathways, Biomarkers, and Interventions
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2022 Genes, Environments and Development in Pain: Crossing the Translational Divide
Biomarkers of Vulnerability and Resilience to Chronic Pain Following Early Life Adversity. A Longitudinal Imaging Study in Mice
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Comorbid Chronic Pain, Mood, and Metabolic Disorders Arising from Early Life Stress Exposure in Mice
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Twin Studies as a Tool to Understand Adolescent Pain
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Mechanistic Brain-Based Treatments for Chronic Pain
Biobehavioral Interventions Targeting Learning-Related Alterations in Brain Circuits
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Brain-Based Treatments Targeting Aberrant Sensorimotor Cortex Excitability in the Transition to Chronic Pain
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Neurofeedback Treatment to Modulate Sensorimotor Cortical Representation of Phantom Limb Pain
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Pain Sensitivity and Chronic Pain During Critical Periods in Life- Studies in Neonatal, Adolescents and Elderly
Pain and Injury in Childhood: Impact on Somatosensory Function
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Epigenetics and Pain in Older Adults
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Phenotyping Pain Mechanisms in Low Back Pain: Modulatory Factors and Clinical Utility
Pro-Nociceptive and Anti-Nociceptive Mechanisms in Spinal Pain
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Mapping Mechanistic and Clinical Pain Phenotypes to Treatment and Outcomes in LBP
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Can Nociceptive, Neuropathic or Nociplastic Phenotypes be Identified in Musculoskeletal Pain?
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Skin Biopsy: From a Diagnostic Tool to a Powerful Asset for Basic and Translational Research in Peripheral Neuropathic Pain
Skin Biopsy: From a Diagnostic Tool to a Powerful Asset for Basic and Translational Research in Peripheral Neuropathic Pain
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Roles of Keratinocytes in Cutaneous Neuropathic Pain
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Neuron-Keratinocyte Communication in the Epidermis in Painful Diabetic Neuropathy
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Translational Evidence for Pain-Cognition Interactions: Insights from Laboratory Animal, Human Experimental and Clinical Studies
Pain-Cognition Interactions in Healthy Individuals: Evidence for a Rewards-Based Resource Competition
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Mechanisms of Pain-Related Decision-Making, Prediction Errors, and Learning in Acute and Chronic Pain
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Lessons for Clinicians and Researchers Across the Lifespan: What Acute Pain Research With Young Children Can Teach Us All
Lessons for Clinicians and Researchers Across the Lifespan: What Acute Pain Research With Young Children Can Teach Us All
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Neuronal Interactions with Microbes in Pain and Host Defense
Neuronal Interactions with Microbes in Pain and Host Defense
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Basic and Clinical Research Exploring Acupuncture Therapy for Pain
Effectiveness and Cost-Effectiveness of Acupuncture
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Basic, Mechanistic, and Clinical Research Exploring Acupuncture Therapy for Pain: an NIH perspective
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Neuroimaging Somatosensory and Psychosocial Mechanisms Underlying Acupuncture
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From Gut Feelings to Memories of Visceral Pain: Mechanisms and Clinical Perspectives for Disorders of Gut-Brain Interactions
Neurobiology of Visceral Pain Disorders as Biopsychosocial Disorders of Gut-Brain Interaction
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From Pavlov to Pain Associative Learning and Extinction of Visceral Pain-Related Fear in Health and Patients with Chronic Visceral Pain
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Large-Scale Studies Elucidating Pain and Sensitivity in a Life-Course
Pain and Pain Sensitivity in Large-Scale Population Based Data: Age and Sex Related Differences
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Sexual Development, Pain History and Pain Sensitivity Assessed in Adolescents from the General Population
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Prospective Analysis of Experimental Pain Sensitivity as a Risk Factor for Chronic Pain
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Molecular Pathophysiology of Pain Resolution
Neuroprotectin D1 and GPR37 in the Resolution of Pathological Pain via Neuroimmune Regulation
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Chemokines and Lipid Mediators Modulate the Resolution of Inflammatory Arthritis Pain
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Neurobiological Mechanisms and Clinical Relevance of Stress-Pain Interactions
Interactions Between Pain and Stress: Role of the Cannabinoid and Opioid Systems
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Exploring Triggers of the Stress Response and its Association with Pain Outcomes in Various Chronic Pain Populations
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Pain in Osteoarthritis
Biopsychosocial Contributions to Osteoarthritis Pain: Current Understanding and Future Directions
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Local Disease Processes in the Joint Contributing to Osteoarthritis Pain
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Pain in Osteoarthritis - Current Knowledge and Future Directions
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Utilization of Pain Biomarkers as the Basis for Decisions in the Therapeutic Development Process and in Clinical Practice: New Approaches from INTEGRATE-Pain
Back Translation of Functional, Pharmacodynamic Pain Biomarkers into Rodents
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Signature for Pain Recovery IN Teens (SPRINT): Biomarker Signature Detection in a Multivariate Dataset Leveraging Supervised Machine Learning Algorithms
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Which Structural and Functional Changes in Skin Nociceptors Cause Chronic Pain?
Axon Guidance Cues That May Play a Role in the Development of Small Fiber Pathology
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C-fiber Specific Electrical Stimulation Paradigms that Differentially Activate Skin Nociceptor Subpopulations and Detect Activity-Dependent
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William D. Willis, Jr., M.D., Ph.D. Memorial Lecture Award: Using Molecular Profiling to Understand Heterogeneity of Nociceptors
William D. Willis, Jr., M.D., Ph.D. Memorial Lecture Award: Using Molecular Profiling to Understand Heterogeneity of Nociceptors
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Nonopioid Analgesics Discovery and the Valley of Death - EMA401 from Concept to Clinical Trial
Nonopioid Analgesics Discovery and the Valley of Death - EMA401 from Concept to Clinical Trial
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From Cells to Humans' Pain (and back) - Translational Pain Research is More than Just a Vision
Using Human Molecular Neuroscience to Increase the Translational Potential of Preclinical Pain Research
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Innovations and Advances in Modelling and Measuring Pain in Animals and Comparisons to Humans
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Novel Biomarkers in Painful Neuropathies - Recent Advances in Magnetic Resonance Imaging (MRI), Microneurography, and Non-Coding RNAs
Magnetic Resonance Imaging Biomarkers in Painful Neuropathies: A Focus on Diabetic Neuropathy and other Symmetrical Polyneuropathies
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Non-Coding RNAs as Hub Regulators of Neuropathic Pain and Neuroregeneration
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Pain, Substance use Disorders and Suicide: Risk Assessment and Mitigation
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Pain, Substance Use Disorders and Suicide: Epidemiology, Theory, Assessment and Mitigation
Cognitive Behavioral Therapy for Suicide Prevention
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Mental Defeat as a Pain-related Psychosocial Predictor of Suicidality in Chronic Pain
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Taking, Processing, Analyzing, Learning: Skin Punch Biopsies - More than Just Fiber Count
Clinical and Research Aspects of Skin Biopsies
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How to Take and Process a Skin Biopsy Following Published Guidelines
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The Intersection of Pain and the Opioid Epidemic Across the Lifespan: Scalable Behavioral Solutions
Modifiable Contributors to Initiation of Misuse of Prescription Opioids for Acute Pain During Adolescence
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Effective and Scalable Behavioral Interventions for Acute and Chronic Pain in Adults with Opioid Use and Misuse
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Understanding the Complexity of Painful Chronic Inflammatory Diseases
Chronic Inflammatory Diseases and Pain
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Pain Mechanisms in Rheumatoid Arthritis: Overlap and Distinguishing Characteristics Compared to other Chronic Pain Conditions
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Tailoring Treatment Strategies to the Patient Experience of Pain in Inflammatory Bowel Disease
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Conditioned Pain Modulation (CPM): To Be or Not to Be?
Conditioned Pain Modulation is a Real Physiological Phenomenon: Evidence for a Spinal Neuronalcorrelate in Translational Studies
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Conditioned Pain Modulation is Associated with Reliability Issues, Problems with Generalizability and Lacks Clinical Predictability
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Demystifying Mechanisms of Placebo Effects Across the Lifespan
Leveraging Mindsets to Ethically Harness the Placebo Effect in Adults and Youth
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Age, Sex and Race Effects on Placebo Analgesia: Results from a Large Cohort Study in Chronic Pain and Healthy Participants
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Increasing the Capacity for Delivering Interdisciplinary Pain Management in Southeast Asia: A Model for Lower Resource Regions
The IASP Multidisciplinary Pain Center Toolkit Project
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Developing a Generic Pain Self-Management Course for Multidisciplinary Health Care Providers using a Competency-Framework
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Indonesian Participation in the Multidisciplinary Pain Clinic Toolkit Project and Pain Self-Management Skills Training for Health Care Professionals
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Introducing Optical Imaging Advances to Unravel Chronic Pain Mechanisms
Long-Term Imaging of Neuronal and Non-Neuronal Spinal Cord Cells in the Awake, Behaving Mouse
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Decoding Cortical Ensembles of Acute Pain and their Reorganisation in Chronic Pain
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Encoding and Transmission of Information by Primary Sensory Afferents
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Novel Peripheral Mechanisms of Neuro-immune Crosstalk in Chronic Pain
The Role of Adipocytes in Chronic Pain and Inflammation
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B Cell Regulation of Neuropathic Pain
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Keratinocytes and Intra-Epidermal Nerve Endings: Two Close Nociceptive Transducers
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Promoting the Engagement of Patient Partners in the Planning, Conduct and Knowledge Translation of Clinical Pain Research: Findings and Consensus Recommendations from the 2021 International Multi-Stakeholder IMMPACT Meeting
Meaningful and Effective Patient Engagement in Clinical Pain Research: Definitions, Shared Values and Guiding Principles
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IMMPACT 2021 Consensus Recommendations for Promoting the Inclusion of Patient Partners Across the Clinical Pain Research Life Cycle and Measuring its Impact
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Stress, Pain and Reward, Evolving Neuroscience with Therapeutic Implications
Stress, Pain and Reward Interactions and Their Clinical Relevance
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Brain Opioid Circuits Modulating Pain Perception
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Elucidating Pain Mechanism with Venom- Derived Peptides and Natural Toxins: What Doesn't Kill You Might Treat Your Pain
Elucidating Pain Mechanism with Venom- Derived Peptides and Natural Toxins: What Doesn't Kill You Might Treat Your Pain
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