IASP Virtual Series on Pain
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Access the presentations from the IASP Virtual Series on Pain, held September 2020 - March 2021.
Digital Health and Pain Management During the COVID-19 Pandemic: What Have We Learned and How Will Things Change?
Speakers: Robert N. Jamison, PhD, Jennifer Stinson, Rn, PhD, CPNP, FAAN, Christopher Eccleston, PhD
From Media to Medicine: Making Sense of Children’s Pain in Cultural and Medical Contexts
Speakers: Jennifer Stinson, Rn, PhD, CPNP, FAAN, Melanie Noel, PhD, RPsych, Lauren Heathcote, PhD, Carley Ouellette, MSc
Incorporating the Lived Experience of Pain in Research
Speakers: Dawn P. Richards, PhD, Mary O'Keeffe, PhD, Kathryn Birnie, PhD, Katherine Dib
Highlights from the IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia
Speakers: Andrew Sven Cracroft. Rice, MD, Lars Arendt-Nielsen, Dr. Med., PhD, David P. Finn, PhD, Christopher Eccleston, PhD,
Ian Gilron, MD, MSc, Simon Haroutounian, PhD, Nadia Soliman, PhD, Emma Fisher, PhD, Andrew Moore, DPhil, DSc, Alexandra E.C.. Fogarty, MD, Nantthasorn Zinboonyahgoon, MD
How “Neuropathic” is Neuropathic Pain? Thoughts for Basic and Clinical Researchers
Speakers: Franziska Denk, DPhil, MSc, Franziska Karl, Dr. rer. nat.
Is Nocebo Placebo's Evil Twin?
Speakers: Karolina A. Wartolowska, PhD, MD,Luana Colloca, MD, PhD, Martina Amanzio, PhD
Large-scale Research Consortia in Pain: Experiences in Europe, USA and Japan
Speakers: Petra Bloms-Funke, PhD, Masako Hosoi, MD, PhD, André Mouraux, MD, PhD, Barbara Illowsky Karp, MD
Measuring Affective States Across Species in Relation to Pain
Speakers: Vera Baumans, DVM PhD, Lee Niel, PhD, Francoise Wemelsfelder, PhD, Nick Andrews, PhD, Duncan Lascelles, BSc, BVSc, PhD
Neuromodulation for Painful Diabetic Neuropathy: Mechanism of action and clinical approach
Speakers: Sam S. Eldabe, MB, ChB, John Markman, MD, Helena Knotkova, PhD, PhilD, Bert Joosten, PhD, Eellan Sivanesan, MD
Pain: Don't Go It Alone
Speakers: Joletta Belton, MSc, Mary Wing, Grad.Dip/Chronic Condition Management, Jenny Bennett, BA(Hons) Dip Ed,
Virginia McIntyre, BA, MRT(R) (MR)
Pharmacokinetic and Pharmacodynamic Considerations in Animal and Human Analgesic Studies
Speakers: Simon Haroutounian, PhD, Albert Dahan, MD, PhD, Garth T. Whiteside, MBA, PhD
Translation in Pain Research – A Two-Way Street in Need of More Travel
Speakers: Petra Schweinhardt MD, PhD, Michael Gold, PhD, Laura S. Stone, PhD
Why Don’t Patients Do What I Tell Them to? The art and Science of Healthcare Communication
Speakers: Blair Smith, MD, MEd, Joletta Belton, MSc, Mike Stewart, MSc BSc (Hons)
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Digital Health and Pain Management During the COVID-19 Pandemic: What Have We Learned and How Will Things Change?
Open to view video.
Open to view video.
The COVID-19 pandemic has been profoundly felt by those seeking or receiving chronic pain treatment. Patients are at risk of severe and debilitating sequelae, without needed services for recovery (i.e., developing new behaviors designed to enhance coping and quality of life) due to halting in-person care and a slow pivot to virtual care. While virtual care models (e.g., telehealth) and web and smartphone pain applications show efficacy, their implementation has been sporadic. This workshop will present a discussion on what was learned in caring for persons with chronic pain during the global pandemic.
Faculty:
Robert N. Jamison, PhD
Jennifer Stinson, Rn, PhD, CPNP, FAAN
Christopher Eccleston, PhD
From Media to Medicine: Making Sense of Children’s Pain in Cultural and Medical Contexts
Open to view video.
Open to view video.
From birth, pain is an inevitable and prevalent experience. How pain is experienced in childhood sets the stage for pain and healthcare experiences well into adulthood. Children’s pain is experienced in, and strongly influenced by, their social context. How children’s pain is displayed in popular media, and how it is explained and communicated by medical providers, has a powerful influence on how pain is understood and experienced. Nevertheless, little research attention has been paid to the influences of popular media and the clinical encounter on pediatric pain and the meaning of these influences for people with lived experience. This workshop will address these gaps and push forward the conversation about these pivotal socio-cultural influences on children’s pain.
Faculty:
Jennifer Stinson, Rn, PhD, CPNP, FAAN
Melanie Noel, PhD, RPsych
Lauren Heathcote, PhD
Carley Ouellette, MSc
Incorporating the Lived Experience of Pain in Research
Open to view video.
Open to view video.
In this session, researchers and patient advocates will talk about their experiences in research, clinical guidelines, and treatment programs. As the importance of involving people with lived experience (patient partners) in the co-creation of research protocols, guidelines, and treatment grows around the world, effective partnerships will be crucial to developing better research and clinical outcomes. This session will provide attendees with best practices and lessons learned that can be incorporated into the research and clinical practice of attendees.
Faculty:
Dawn P. Richards, PhD
Mary O'Keeffe, PhD
Kathryn Birnie, PhD
Katherine Dib
Highlights from the IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia
Open to view video.
Open to view video.
The workshop opened with the task force Chair (Andrew Rice) giving an introductory overview of the work of the task force and the IASP Position Statement.
Speakers:
Andrew Sven Cracroft. Rice, MD FRCP FRCA FFPMRCA FFPMCAI
Lars Arendt-Nielsen, Dr. Med., PhD
David P. Finn, PhD
Christopher Eccleston, PhD
Ian Gilron, MD, MSc, FRCPC
Simon Haroutounian, PhD
Nadia Soliman, PhD
Emma Fisher, PhD
Andrew Moore, DPhil, DSc, CChem FRSC
Alexandra E.C.. Fogarty, MD
Nantthasorn Zinboonyahgoon, MD
How “Neuropathic” is Neuropathic Pain? Thoughts for Basic and Clinical Researchers
Open to view video.
Open to view video.
Our field generally groups pathophysiological pain into neuropathic and inflammatory, a useful dichotomy from a diagnostic standpoint. Yet, it is well-known that neuropathic lesions and any consequent peripheral sensitization are substantially driven by pro-inflammatory mediators. How do these two facts fit into one cohesive framework? Our nomenclature biases us to assume that neuropathic pain is somehow “less inflammatory” than inflammatory pain; however, is this actually supported by evidence?
Our live workshop at IASP will examine this question in a series of talks, but for our virtual workshop we instead want to hear from you! Are you a basic or clinical researcher? A clinical practitioner? A patient or patient expert? Do you think of some types of pain as more or less inflammatory than others? What classifications are most useful to you in terms of diagnosis/ when deciding on treatment options? Do you think about neuropathic versus inflammatory pain models in your research?
Faculty:
Franziska Denk, DPhil, MSc, BA
Franziska Karl, Dr. rer. nat.
Is Nocebo Placebo's Evil Twin?
Open to view video.
Open to view video.
The nocebo effect refers to worsening of symptoms or adverse events that are related either to the use of placebo or to the active treatment, caused by factors such as negative suggestions, past experiences, and misattribution, but not the pharmacological or physiological effects of the therapy. Unlike placebo, which can be used to help to relieve symptoms or potentiate the effect of a treatment, nocebo is always unwanted. Nocebo may make a treatment look ineffective or harmful, and, therefore, it distorts the treatment effect in clinical practice, in biomedical experiments, and clinical trials.
Faculty:
Karolina A. Wartolowska, PhD, MD
Luana Colloca, MD, PhD
Martina Amanzio, PhD
Large-scale Research Consortia in Pain: Experiences in Europe, USA and Japan
Open to view video.
Open to view video.
Funding agencies and public-private partnerships in Europe, the U.S.A. and Japan have enhanced their engagements to boost innovation by coordinating multi-disciplinary approaches between all key stakeholders in pain R&D and healthcare. The speakers will share their experiences in building large-scale consortia: the European IMI-PainCare project of the Innovative Medicine Initiative (IMI), the NIH’s Helping to End Addiction Long-Term (HEAL) Initiative and two of its programs, the Preclinical Screening Platform for Pain (PSPP) and the Early Phase Pain Investigation Clinical Network (EPPIC-NET), and a research project funded by the Japan Agency for Medical Research and Development (AMED).
Different perspectives on the challenges and learnings will be reflected. Furthermore, the speakers will emphasize valuable synergies which will arise from interactions between these programs, enabling a trans-continental consensus. It will be critically discussed which collaborative efforts are still needed to further the science in chronic pain.
Faculty:
Petra Bloms-Funke, PhD
Masako Hosoi, MD, PhD
André Mouraux, MD, PhD
Barbara Illowsky Karp, MD
Measuring Affective States Across Species in Relation to Pain
Open to view video.
Open to view video.
The affective component of pain is a significant contributor to the more global experience of patient suffering. Opioids alleviate the negative affective component of pain and make the pain less aversive. However, affective state is not just a product of pain, it can also be a driver of pain. Pre-surgical catastrophizing reliably predicts a higher self-reported pain score after the surgery. A number of interventions to reduce pre-surgical anticipatory anxiety successfully modify post-surgical pain in a variety of patient populations. Beyond traditional measures of evoked stimuli, the ability to study the bidirectional relationship between pain and affective state in animal models requires new tools be added to the in-vivo scientist’s toolbox. The theory and data supporting the value of affective state measurements in animal models of pain will be explored, including introduction to several methods of evaluating affective state, in several common pre-clinical animal model species: mouse, rat, dog, and pig.
Faculty:
Vera Baumans, DVM PhD DipECLAM
Lee Niel, PhD
Francoise Wemelsfelder, PhD
Nick Andrews, PhD
Duncan Lascelles, BSc, BVSc, PhD, MRCVS, CertVA, DSAS(ST), DECVS, DACVS
Neuromodulation for Painful Diabetic Neuropathy: Mechanism of action and clinical approach
Open to view video.
Open to view video.
Diabetic peripheral neuropathy (DPN) is a common, debilitating and distressing complication of diabetes. Most patients develop painless, insensate distal nerve damage which increases the risk of foot ulceration and subsequent amputation. Amputation is not only devastating in its impact on the person with diabetes and their family, leading to loss of independence and livelihood; it is also very expensive in material terms and results in only 50% surviving for two years. Around a quarter of all diabetic patients also develop a chronic painful condition mainly affecting the legs which can result in considerable disability and suffering. Many such patients with painful DPN have depression, anxiety, fear and stress, and do not sleep well. There is thus an urgent need to detect DPN early by using objective, validated point-of-care devices (e.g. in a one-stop microvascular screening service) as clinical exam or the use of the 10 gram monofilament is not reliable. Early detection will lead to an earlier intervention to reduce risk factors for the development of DPN.
Faculty:
Sam S. Eldabe, MB, ChB FRCA FFMPRCA
John Markman, MD
Helena Knotkova, PhD, PhilD
Bert Joosten, PhD
Eellan Sivanesan, MD
Pain: Don't Go It Alone
Open to view video.
Open to view video.
In accordance with the IASP’s Global Year for the Prevention of Pain, this workshop will describe the relevance and importance of peer support in chronic pain management. Peer support is a part of the jigsaw that constitutes multidisciplinary management of chronic pain. It can help to prevent pain patients from losing the progress they have made in managing their pain and support them to continue to manage in the best way they can. Presentations will raise the awareness of how peer-led support groups can offer education and self-management strategies for chronic pain patients, along with valuable social interaction. Peer support is an under-utilized area in pain management, however there is evidence of increased self-efficacy and improved quality of life for not only chronic pain, but many other chronic conditions.
Faculty:
Joletta Belton, MSc
Mary Wing, Grad.Dip/Chronic Condition Management
Jenny Bennett, BA(Hons) Dip Ed
Virginia McIntyre, BA, MRT(R) (MR)
Pharmacokinetic and Pharmacodynamic Considerations in Animal and Human Analgesic Studies
Open to view video.
Open to view video.
This workshop will provide an introduction on the importance of pharmacokinetic (PK) and pharmacodynamic (PD) considerations in studies of analgesic medications in animals and humans. Drug PK parameters determine the concentration of a drug in plasma, and in the tissue of interest. The relationship between a drug’s concentration at its cellular/molecular target, and its pharmacological effect (i.e. pharmacodynamics) are critically important for determining the efficacy and safety profiles of each drug. Unfortunately, in pain research in general, and in preclinical research in particular, comprehensive pharmacokinetic characterization of experimental drugs is seldom performed, while claims of efficacy and safety are being made.
Faculty:
Simon Haroutounian, PhD
Albert Dahan, MD, PhD
Garth T. Whiteside, MBA, PhD
Translation in Pain Research – A Two-Way Street in Need of More Travel
Open to view video.
Open to view video.
In this workshop, the challenges as well as the potential gains of translational pain research will be discussed and concrete examples of successful and unsuccessful translational pain research from different pain conditions and different perspectives will be given.
Faculty:
Petra Schweinhardt MD, PhD
Michael Gold, PhD
Laura S. Stone, PhD
Why Don’t Patients Do What I Tell Them to? The Art and Science of Healthcare Communication
Open to view video.
Open to view video.
In this session we will identify some of the barriers to effective communication between patients and healthcare professionals, including clinicians and researchers. We will then explore various solutions that will help ease the understandable frustrations felt by healthcare professionals and patients alike. This session goes beyond dialogue and checklists, expounding upon how to listen to understand, the value of meaningful conversations that can facilitate change, and how to co-create new, more therapeutic narratives that help patients make sense of their pain in ways that make both biological and biographical sense. We will explore how to guide patients to new understandings of their pain and what can be done, including what they can do, about it.
Faculty:
Blair Smith, MD, MEd, FRCGP, FFPMRCA, FRCP
Joletta Belton, MSc
Mike Stewart, MSc BSc (Hons) MCSP SRP PG Cert (Clin Ed)
Evaluation
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