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Contains 3 Component(s) Includes a Live Web Event on 09/24/2026 at 11:00 AM (EDT)
Presented by Global Year 2026 Task Force Members and Invited Presenters.
This webinar will take place on September 24, 2026, at 11:00 am EDT. This webinar is free to all.
This webinar is Part 2 of Translational Science in Neuropathic Pain: The State of the Art.
Webinar Overview:
Understanding neuropathic pain requires approaches that bridge mechanistic discovery and clinical relevance. In this second session of the Translational Science in Neuropathic Pain webinar series, leading experts present cutting‑edge insights into how human‑based methodologies are reshaping our understanding of neuropathic pain mechanisms and opening new avenues for diagnosis and therapy.
The webinar will highlight advances in the study of human peripheral sensory neurons using complementary translational strategies. Ted Price will present landmark work from human dorsal root ganglion and peripheral nerve tissue obtained from surgeries and organ donors, demonstrating how nociceptor hyperexcitability and neuronal degeneration contribute to chronic neuropathic pain. By integrating electrophysiological, molecular, and ‑omic analyses, this work provides direct evidence from human tissue that links cellular dysfunction to clinical pain phenotypes and therapeutic targets.
Jordi Serra will focus on microneurography, a unique electrophysiological technique that enables direct recording of action potentials from peripheral nerves in awake humans. His talk will illustrate how microneurography has advanced our understanding of abnormal nociceptor activity in neuropathic pain and how it serves as a powerful translational bridge from bench to bedside, with growing relevance for the diagnosis and stratification of small fiber neuropathies and chronic pain syndromes.
Manuela Schmidt will present systems‑level approaches to translational pain research, highlighting how advanced proteomics and metaproteomics can uncover molecular pathways underlying chronic pain. Her talk will emphasize the integration of human biospecimens—including blood, stool, and dorsal root ganglia—with systems biology approaches to explore host–microbiome interactions and their relevance for pain mechanisms and therapeutic development.
Together, these presentations showcase how human‑centered experimental strategies from tissue‑based molecular profiling to in vivo nerve recordings are transforming neuropathic pain research and accelerating translation into clinically meaningful insights and treatments.
Moderators:
Angelika Lampert – Germany
Diana Tavarres - United States
Daniela Maria Menichella - United States
Patrick Dougherty - United States
Presenters:
Jordi Sierra - United States
Manuela Schmidt - Austria
Ted Price - United States
$i++ ?>Jordi Serra
Department of Clinical Neurophysiology, King’s College Hospital, London, UK.
Since 2014, Dr. Serra has been a Consultant in Neurology and Clinical Neurophysiology at King’s College Hospital, London. Jordi Serra received his medical degree in 1988 from the University of Barcelona and completed his Neurology specialty in 1992 in Barcelona. He spent following years (1992 – 1995) as a Neuromuscular Fellow at the Neuromuscular Unit, Good Samaritan Hospital and Oregon Health Sciences University in Portland, Oregon, USA, where he specialized in the study, diagnosis and treatment of neuropathic pain patients.
During this period, he was trained in the technique of microneurography. Microneurography offers an unrivaled tool to study spontaneous pain in humans by producing objective records of the abnormal nerve impulse activity responsible for paresthesia (myelinated fibers) and spontaneous pain (unmyelinated fibers). This is the only available technique to detect and quantify positive sensory phenomena of peripheral nerve origin in humans by recording individual action potentials from single sensory fibers.
Dr. Serra’s pioneering work on the recording of abnormal spontaneous activity in C-nociceptors from patients and animal models of neuropathic pain is widely cited in medical literature. Currently, he is researching the correlation of peripheral nociceptor spontaneous activity as seen in patients with the perceptual experience of ongoing pain.
Dr. Serra’s expertise also lies in the areas of electromyography, nerve conduction studies, evoked potentials, quantitative sensory testing, thermography, and intraoperative electrophysiological monitoring.
He cofounded both the Pain section of the American Academy of Neurology and the Neuropathic Pain Group of the Spanish Society of Neurology, where he served as the first Chairman. He is a member of the International Association for the Study of Pain (IASP), the British Society of Clinical Neurophysiology, the Spanish Society of Neurology, and the Spanish Pain Society.
Dr. Serra has authored many scientific journal articles and book chapters. He is a frequently invited speaker and organizes courses on neuropathic pain. He also serves as a reviewer for several scientific journals.
$i++ ?>Manuela Schmidt
Professor of Pharmacology and Toxicology & Vice Dean for Research
University of Vienna
Manuela Schmidt completed her PhD at the International Max Planck Research School for Neurosciences in Göttingen (Germany) in 2006. She subsequently joined the laboratory of Prof. Ardem Patapoutian at The Scripps Research Institute in La Jolla, California, where she investigated TRP and Piezo2 ion channels. She went on to establish an Emmy Noether-funded research group at the Max Planck Institute for Experimental Medicine in Göttingen, focusing on the systems biology of pain. In 2020, she was appointed Full Professor of Pharmacology and Toxicology at the University of Vienna, where she also serves as Vice Dean for Research at the Faculty of Life Sciences.
$i++ ?>Ted Price
Ashbel Smith Professor
University of Texas at Dallas
Theodore (Ted) Price is Ashbel Smith Professor in the Department of Neuroscience at the University of Texas at Dallas, where he is the Director of the Center for Advanced Pain Studies. Ted did his PhD with Ken Hargreaves at UT Health San Antonio and his postdoc with Fernando Cervero at McGill. Ted started his independent lab in 2007 at the University of Arizona and moved to UT Dallas in 2014. Ted’s lab’s goal is to identify molecular mechanisms causing chronic pain with emphasis on developing new drugs to treat pain. His lab’s focus is on human molecular neuroscience with specialization in the dorsal root ganglion and spinal dorsal horn. Ted has published more than 250 peer-reviewed studies and has been continuously funded by NIH for more than 15 years. He is a co-founder of many companies, including 4E Therapeutics.
$i++ ?>Angelika Lampert, MD (Moderator)
Professor for Neurophysiology
Institute of Neurophysiology at RWTH Aachen University
Angelika Lampert, MD, is the Director of the Institute of Neurophysiology at RWTH Aachen University, Germany. She coordinates the Sodium Channel Network Aachen and serves as speaker of the Scientific Center for Neuropathic Pain Aachen (SCNAACHEN), focusing on inherited neuropathic pain syndromes such as small fiber neuropathy linked to sodium channel mutations. Her research emphasizes translational basic science, including patient-derived stem cells, Patch-Seq, sodium channel biophysics, and pharmacology. Angelika is co-chair of the IASP Global Year 2026 on Neuropathic Pain.
$i++ ?>Daniela Maria Menichella, MD, PhD (Moderator)
Associate Professor
Northwestern University in Chicago
Daniela Maria Menichella, MD, PhD, is an Associate Professor of Neurology and Pharmacology at Northwestern University in Chicago. She directs the Peripheral Neuropathy Multidisciplinary Clinic and the Charcot-Marie-Tooth Association Center for Excellence. Dr. Menichella provides care for patients suffering from neuropathic pain due to peripheral neuropathy. In addition to her clinical work, she is actively involved in basic and translational research and takes part in NIH NeuroNext and NIH HEAL EPICC clinical trials. Her research focuses on the molecular and cellular mechanisms that underlie neuropathic pain and axonal degeneration in both hereditary and acquired peripheral neuropathies, with a particular emphasis on painful diabetic neuropathy. Her laboratory utilizes an integrated approach that combines pain behavioral testing, electrophysiology, in vitro and in vivo calcium imaging, confocal microscopy, chemogenetics, and single-cell RNA sequencing, using conditional and transgenic mouse models. Recently, her lab has begun to validate therapeutic targets using human tissue, such as dorsal root ganglia (DRG) and skin biopsies from patients with well-characterized painful peripheral neuropathies.
$i++ ?>Diana Tavares Ferreira, PharmaD/MS, PhD (Moderator)
Assistant Professor
University of Texas at Dallas
Diana Tavares Ferreira, PharmD, MS, PhD, is Assistant Professor of Neuroscience at the University of Texas at Dallas. She earned her PharmD and MS degrees from the University of Coimbra and completed her PhD in Neuroscience at the University of Sheffield, followed by postdoctoral training at UT Dallas.
Her research focuses on axonal transport, RNA regulation, and plasticity in neurodegeneration, peripheral neuropathies, and chronic pain. She employs a broad range of omics, experimental, and computational approaches to investigate mechanisms underlying nervous system dysfunction.
$i++ ?>Patrick Dougherty, PhD (Moderator)
Professor
The University of Texas MD Anderson Cancer Center & The University of Texas Health Science Center at Houston
Patrick Dougherty, PhD, is Professor in the Department of Pain Medicine–Research at The University of Texas MD Anderson Cancer Center and Professor in the Department of Neurobiology and Anatomy at The University of Texas Health Science Center at Houston.
Throughout his career, his research has focused on understanding the neurochemical and physiological consequences of peripheral nerve injury and inflammation on central nervous system activity. His laboratory’s recent work centers on elucidating the mechanisms of pain in cancer patients, with the goal of identifying interventions for chemotherapy‑induced neuropathic pain and cancer‑related hyperalgesia. This work includes complementary clinical and preclinical studies, combining quantitative sensory testing with skin biopsy to define the specific sensory nerve fibers involved in chronic chemoneuropathy.
His research was among the first to demonstrate that cancer itself can contribute to neuropathy prior to treatment and that pre‑existing differences in distal innervation influence pain vulnerability. More recent studies have characterized anatomic, physiological, and transcriptomic changes in human dorsal root ganglia associated with neuropathic pain, revealing sexually dimorphic molecular mechanisms underlying ectopic neuronal activity and persistent pain.
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Contains 3 Component(s) Includes a Live Web Event on 09/16/2026 at 10:00 AM (EDT)
Presented by Global Alliance of Partners for Pain Advocacy (GAPPA) members.
This webinar will take place on 16 September 2026 at 10:00 am EDT
Free to IASP Members; $25.00 for non-members
This webinar will introduce the role and relevance of lived experience in the development, conduct, dissemination, and implementation of pain research. It will describe recent work in this area, including the establishment of the Global Alliance of Partners for Pain Advocacy (GAPPA). We will discuss the ways in which people with lived experience of pain collaborate with researchers, the barriers and facilitators to such co-creative work, and how people with lived experience of pain, clinicians, and researchers – together – can help to improve our understanding of pain and the lives of people who live with it. In pain research there is no “them” and “us” – there is only “us”.
Educational Objectives
After attending this webinar, participants will have developed their understanding of:
1. the importance of lived experience in pain research
2. barriers and facilitators for contributing lived experience to pain research
3. the development and role of GAPPA in addressing these issuesModerator
Dawn Gibson
Presenters
Joletta Belton, Pain Advocate, Past Co-Chair of GAPPA.
Blair H. Smith MD, University of Dundee, Past Co-Chair of GAPPA.
Dawn Gibson, Pain Advocate.$i++ ?>Joletta Belton, MSc
Advocate
Independent Patient Advocate
Joletta is a fierce advocate for the integration of lived experience into the research, study, and treatment of pain. She came to this work through her own experiences of living with chronic pain and struggling to find adequate care, resources, and support after an on-the-job injury as a firefighter. She began writing a blog to try and make sense of things, which led to invitations to speak at conferences and to partner in pain research, education, and publishing.
She was invited to a meeting at the 2018 World Congress on Pain to discuss how IASP could meaningfully integrate lived experience into its work. In 2019, the Presidential Task Force that became the Global Alliance of Partners for Pain Advocacy (GAPPA) was formed, and Joletta became the founding Co-Chair with Blair. She currently serves as GAPPA Past Co-chair.
$i++ ?>Blair H. Smith, MD
Professor
University of Dundee
Blair H. Smith MD, FRSE, Professor of Population Health Science at the University of Dundee (Scotland), recently also retired as Consultant in Pain Medicine. Graduating at the Universities of Glasgow (MBChB, 1987) and Aberdeen (MEd Distinction 1998; MD 2000), he held an NHS Primary Care Career Scientist Award (2000 to 2005) and was Professor of Primary Care Medicine at the University of Aberdeen until 2011 before taking up his current post.
His research on chronic pain and neuropathic pain has been published widely, specifically studying its epidemiology, genetics, primary care management and self-management. He has published >320 peer-reviewed research papers, various book chapters and reports, and two volumes of poetry. He has been listed in the Web of Science as a “highly cited researcher” (top 0.1% globally) from 2020 to 2024 (Scopus h-Index 88), and has been (co-)investigator on research grants totalling >£28.3M. In 2025 he was given biennial the Lady Margaret MacLellan Award for outstanding contribution to medical research in Scotland. He was a founding Co-Chair of GAPPA, with Joletta and continues to serve as Past Co-Chair.
$i++ ?>Dawn Gibson (Moderator)
Dawn Marie Gibson is a former youth and young adult lay chaplain turned artist, organizer, and citizen lepidopterist. Before joining the National Pain Advocacy Center's leadership she led the Spoonie Chat Twitter community, supporting her fellow spondyloarthritis and fibromyalgia folks and other chronic pain patients through health social media, media availability, and policy advocacy centering the lived experience of patients and the people who love them.
She has extensive family caregiving experience in medical and surgical oncology, dementia, and end-of-life care. She lives in Michigan with her family and a cadre of hand-raised butterflies.
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Contains 3 Component(s) Includes a Live Web Event on 09/08/2026 at 10:00 AM (EDT)
Presented by Pain in Intellectual and Developmental Disabilities (PIDDSIG)
This webinar will take place on Wednesday, 8 September 2026, at 10:00 a.m. EDT.
Free to IASP Members; $25.00 for non-members
Webinar Overview
Pain provides an essential warning system that protects us from harm. It exists in tandem with the tactile system, that together, enable us to safely and richly experience the world and others. In intellectual and developmental disabilities these systems can be affected, disrupting that safe and nurturing physical connection with the world and others. This 60-minute webinar, hosted by the Pain in Intellectual and Developmental Disabilities SIG brings together researchers investigating rodent models of these conditions. This works aims to further understanding of pain mechanisms in intellectual and developmental disabilities with the goal of improving pain management for affected individuals.
Learning Objectives:
- An appreciation of environmental and genetic rodent models of intellectual and developmental disabilities
- An understanding of behavioural phenotypes observed in these models and relation to clinical phenotype
- An understanding of mechanisms that underlie phenotypes in these modelsModerator:
Dr Brian McGuire.
Presenters:
Dr Carole Torsney, Reader, University of Edinburgh.
Dr Michelle Roche, Reader, University of Galway.
$i++ ?>Dr. Carole Torsney
Reader
University of Edinburgh
Carole Torsney is a Reader at the University of Edinburgh and is based in the Institute for Neuroscience and Cardiovascular Research. She is a member of the Simons Initiative for the Developing Brain and the Simons Foundation Autism Rat Models Consortium. She received her PhD under the supervision of Professor Maria Fitzgerald at University College London. She then did postdoctoral training at Columbia University, New York, before establishing her lab at the University of Edinburgh. Her research investigates the nervous system processing of pain and touch, and how this can differ between the sexes. She is specifically interested in the plasticity that underlies chronic pain conditions and the altered pain and tactile reactivity that manifests in neurodevelopmental disorders.
$i++ ?>Dr. Michelle Roche
Associate Professor in Physiology and Co-Director
Centre for Pain Research at the University of Galway
Dr Roche is an Associate Professor in Physiology and Co-Director of the Centre for Pain Research at the University of Galway, Ireland. Her research interests focus on enhancing understanding of the neurobiology and pathophysiology underlying pain, mood disorders, autism and their interactions. She has a particular interest sex differences and the role of the neuro-immune, endocannabinoid and opioid systems. Her research Her research has resulted in over 80 research manuscripts, reviews and book chapters and supported by EU, national and industry funding. Dr Roche is currently European Pain Federation EFIC council member and immediate past-president of the Irish Pain Society (2023-2025). Dr Roche has contributed to and lead on several international networks including as scientific coordinator for PAINDIFF and Enlight PainNet and as the Scientific Communications Coordinator for EU-SABV Cost Action. She is an Editorial Board member of several international scientific journals including Frontiers in Pain Research and Neuropharmacology.
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Contains 4 Component(s)
Presented by Pain and Trauma Special Group of Interest
This webinar took place on 29 July 2026 at 03:00 pm.
Free to IASP Members and Non-Members.
In this webinar, Dr Jill Zelin and Dr Felicity Saunders shared their experience of leading the My Body Back™ clinic, speaking to the research conducted to set up the clinic and practical tips of running a specialist trauma informed service from both a medical and psychological perspective. Jill and Felicity talked about how vulval pain presents in sexual health services and share clinical examples of how this are assessed, diagnosed and treated. Finally, Jill and Felicity aimed to speak of their hopes for trauma informed support for vulval pain in future.
Moderator
Clair Jacobs
Presenters
Dr. Felicity Saunders
Dr. Jill Zelin
$i++ ?>Clair Jacobs, MSc (Moderator)
Vice-Chair of Pain and Trauma SIG
INPUT Pain Management, St Thomas’s NHS trust
Clair is a Consultant Physiotherapist. Physiotherapy Clinical Lead in Pain Management at Guys and St Thomas’ NHS Trust, Senior Lecturer in Advanced Physiotherapy Practice, Brunel University, London, UK. She also works with Freedom from Torture, UK, She holds national and international positions as Vice-Chair of the Pain and Trauma Special Interest group IASP and Co-Chair of the Physiotherapy Pain Association. Clair has 30 years of experience as a clinician, manager, and educator, both within the NHS and Internationally. She is a graduate of Narrative Medicine and an accredited and experienced facilitator in narrative based and psychologically informed approaches. She has recently published a service evaluation on 'Patient perceptions in relation to trauma-informed care on pain management programmes.'
$i++ ?>Felicity Saunders
Senior Clinical Psychologist
London's Barts Health NHS Trust
Dr Felicity Saunders is a Senior Clinical Psychologist specialising in Sexual Health and HIV Medicine at London's Barts Health NHS Trust. She is the lead psychologist for the My Body Back™ Clinic, the only clinic in England offering specialised, trauma-informed healthcare—including cervical screenings and STI testing—designed specifically for survivors of sexual trauma- My Body Back Project - Rape and sexual assault support in London. My Body Back™ has appeared on BBC London News and BBC Radio 4's Women's Hour. Felicity also works privately, using Compassion Focused Therapy (CFT) to support her clients with complex mental health difficulties and finds it a particularly helpful model when working with Trauma and Psychosexual difficulties.
$i++ ?>Jill Zelin
Medical Lead
My Body Back™ Clinic
Dr Jill Zelin is a Consultant in Sexual Health at Barts Health NHS Trust and Medical Lead for the My Body Back™ Clinic London. She has led the development of trauma-informed cervical screening and sexual health services for women and people who have experienced sexual violence, working with NHS and voluntary-sector partners to improve access, choice and psychological safety in care. Her work focuses on survivor-informed service design, inclusive pathways, clinical governance and embedding trauma-informed practice within routine NHS systems
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Contains 4 Component(s)
2026 World Congress on Pain Refresher Courses
Abstract
This refresher course will begin with a review by Dr. Fairbanks of the major analgesic drug classes (e.g., opioids, non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, anticonvulsants and antidepressants), including an overview of their mechanisms
of action, clinical applications and limitations. The remainder of the session will then focus on two rapidly evolving approaches to pharmacological pain management: subtype-selective sodium channel blockers and cannabinoids.
Dr. Lampert will cover the basic physiology of sodium channel function, the main NaV sodium channel subtypes important for peripheral sensory neurons, what we know from genetic disease and how different subtypes convey specific function to sensory neuron subtypes. She will then address how blocking NaVs have been used in acute pain treatment for decades and why the development of the new NaV1.8 blocker Suzetrigine is so important, as it opens the avenue for a new class of therapeutics.
Faculty List:
Dr. Starowicz-Bubak will begin with an update on our current understanding of endogenous and exogenous cannabinoid pharmacology. She will then highlight her work on the role of the endocannabinoid system in the pathophysiology of osteoarthritic joint pain.
Dr. Busse will provide a synthesis of the current clinical evidence and share updated guidelines for the use of cannabis in chronic pain.
Dr. Carolyn Fairbanks, Professor, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
Major analgesic drug classes and mechanisms of action
Dr. Angelika Lampert, Professor, Aachen University & Director of the Institute of Neurophysiology, Aachen, Germany.
Sodium channel blockers – what we know and where we are going
Dr. Katarzyna Starowicz – Bubak Professor & Director, Maj Institute of Pharmacology Polish Academy of Sciences, Krakow, Poland
Endogenous and exogenous cannabinoid pharmacology
Dr. Jason Busse, Professor, Department of Anesthesia, Faculty of Health Sciences, McMaster University & Associate Director of the DeGroote Center for Medicinal Cannabis Research.
Cannabis for Chronic Pain – current evidence and guidelines.
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Contains 7 Component(s)
2026 World Congress on Pain Refresher Courses
Overview
Animal (non-human) models of pain or pain-related outcomes are used widely to advance the science of pain and analgesia. Given the ethical and welfare implications of using non-human animals to study pain, it is imperative that scientists choose models based on a comprehensive understanding of the relative strengths and limitations of the various models in the field. It is also essential for the field of pain research to continue to strive for development of improved, more translationally valid animal models of pain-related outcomes, and to embrace new methodologies and technologies that may facilitate this. This refresher course, delivered by 7 expert speakers from a variety of backgrounds and perspectives (basic science, academia, clinical, industry) will provide a comprehensive overview of the current state-of-the-art regarding animal models of pain-related outcomes.
Educational objectives
· Provide an overview of the variety of animal models of pain or pain-related outcomes available, with consideration of their strengths, limitations, translational relevance and validity.
· Understand tests and paradigms used to assess interactions between pain and mood.
· Appreciate how subject strain, sex and factors in the laboratory environment can influence the results of preclinical pain experiments.
· Discuss the importance of response heterogeneity and multimodal integrated longitudinal approaches for interrogating pain development
· Understand how large animal models can be employed to enrich the translational research paradigm.
· Gain insight into how animal models of pain and pain-related outcomes are used within the pharmaceutical industry.
Faculty list:
Dr. David Finn (Convener), University of Galway, Ireland
Introduction to the refresher course, and overview of animal models of pain-related outcomes
1. Introduce the refresher course and speakers
2. Provide an overview of the variety of animal models of pain-related outcomes available, with consideration of their strengths, limitations, translational relevance and validity.
3. Consider sex as a biological variable in preclinical pain studies
Dr. Michelle Roche, University of Galway, Ireland
Animal models to understand the interactions between chronic pain and mood disorders
1. Understanding what tests and paradigms have been used to assess interactions between mood and pain
2. Strengths and limitations of current paradigms
3. Considerations in choosing the paradigm and model for your research question
Dr. Esther Pogatzki-Zahn, University of Muenster, Germany
Animal models of post-surgical pain, and artificial intelligence/machine learning approaches in preclinical pain research.
1. Review the variety of animal models of post-surgical pain available, with consideration of their strengths, limitations, translational relevance and validity.
2. Consider how artificial intelligence/machine learning approaches can impact on preclinical pain research.
Dr. Jeffrey Mogil, McGill University, Canada
Issues in Algesiometry: Factors affecting preclinical pain models
1. Appreciate how decisions as to subject strain and sex can influence the results of preclinical pain experiments.
2. Appreciate how mismatches between human symptoms and rodent dependent measures can impair translation.
3. Appreciate the multitude of factors in the laboratory environment that can influence the results of preclinical pain experiments.
Dr. Kevin Keay, University of Sydney, Australia
Towards improved translational validity of animal models of pain
1. To evaluate the translational validity of neuropathic pain models
2. To compare models of cranial and post-cranial neuropathic pain
3. To discuss multimodal integrated longitudinal approaches to interrogating neuropathic pain development
4. To discuss the importance of response heterogeneity in neuropathic pain models.
Dr. B. Duncan X. Lascelles, North Carolina State University, USA
Leveraging ‘large’ animals for translational pain research
1. Discuss the pros and cons of leveraging large animals, in particular companion pet animals, for translational pain research.
2. With reference to osteoarthritis persistent pain, the opportunities for modeling the complete human pain experience will be presented and discussed.
3. Focus on validated and ‘in development’ assays that cover all the dimensions impacted by pain.
4. Discuss exciting opportunities for target and mechanism discovery using large animal biological tissues will be discussed. Delegates will leave with an understanding of how large animal models can be employed to enrich the translational research paradigm.
Dr. Carina Stenfors, Orion Pharma, Finland
Advancing analgesic discovery and development with animal models: the pharmaceutical industry perspective
1. Explain the key criteria employed within the pharmaceutical industry when selecting the most appropriate animal model(s) of pain (i.e. what factors guide the choice of model selection)
2. Describe important considerations for how animal models of pain are used within the pharmaceutical industry (i.e. experimental design, sample size, controls etc)
3. Explain the importance of assessing PK-PD relationships within the context of drug discovery and development
$i++ ?>Esther Pogatzki-Zahn
Professor in the Department of Anaesthesiology, Intensive Care and Pain Medicine
University of Muenster, Germany
Esther Pogatzki-Zahn (EPZ) is a professor in the Department of Anaesthesiology, Intensive Care and Pain Medicine at the University Hospital Muenster. She has been trained as an anesthesiologist, is a certified pain specialist and a neuroscientist. She leads the clinical pain service at the University Hospital Muenster, and the „Translational Pain Research“ group. Her research is aiming to provide insight into the neuropathology of postsurgical, pelvic, chronic inflammatory, neuropathic and cancer-related pain by using basic science, in-vivo behavioral, electrophysiological, omics, optogenetic, fMRI and molecular methods. Furthermore, she performs human experimental and clinical pain-related studies encompassing a bio-psycho-social spectrum related to the pain entities mentioned above. She performs systematic reviews and meta-analysis related to pain, regional anesthesia and perioperative medicine (pre-clinical and clinical) including methods to improve their methodology/design. Her work further encompasses the field of Core Outcome Sets. EPZ is involved in many national and international multicenter research projects, for example as a PI (or Co-PI) in IMI-PainCare (www.imi-paincare.eu/), POET-Pain (https://www.poet-pain.de), PANDOS (www.esaic.org/research/research-groups/pandos/), IT-Pain (https://itpain.org/), CHIELDPAIN, among other. Since recently, she is leading StEPP-UPP, a consortium intended to investigate mechanisms of endometriosis-related pain, and GEPARD, a project addressing gender differences in efficacy of treatments for pain after surgery. Her research is supported by grants from the German Research Foundation (DFG), the Federal Ministry of Research, Technology and Space (BMFTR), the Federal Joint Committee (G-BA) and the Innovative Medicines Initiative 2 (IMI). She is president elect of the European Pain Federation (EFIC), was council member of the International Association for the Study of Pain (IASP, from 2018-2024), is executive board member of the German Pain Society, board member of the Acute Pain SIG of the IASP, member of the European Society of Regional Anaesthesia & Pain Therapy (ESRA) PROSPECT group (https://esraeurope.org/pain-management/) and chair of the European Pain Federation (EFIC) Research Group, among others. She is Deputy Editor in Chief for the EJA and EJAIC, section editor for the EJP and reviewer for many international peer review journals. She published more than 190 original peer reviewed manuscripts, more than 50 review articles/ editorials, 16 book chapters and 3 books (h-Index: 61).
$i++ ?>Duncan Lascelles, PhD
Professor
Dr. Lascelles is the Dr. J. McNeely and Lynne K. DuBose Distinguished Professor of Musculoskeletal Health, and Professor of Translational Research in Pain and Surgery. Since his PhD training at Bristol, UK, he has devoted is professional career to improving our ability to recognize and treat pain in animals. His research program (Translational Research in Pain [TRiP]) develops methods to measure pain associated with spontaneous disease in animals and seeks to understand the underlying neurobiology with the goal of improving our understanding of how to control pain in companion animals, and facilitating analgesic development in human medicine.
He is director of the Comparative Pain Research and Education Centre (CPREC). He has authored over 270 peer reviewed research papers and reviews, over 400 research abstracts, and ~ 30 book chapters.
$i++ ?>David Finn, PhD
Professor
University of Galway
David Finn is an Established Professor of Pharmacology and Therapeutics, Principal Investigator, and Founding Co-Director of the Centre for Pain Research at the University of Galway, Ireland. Professor Finn graduated with a BSc (Hons) in Biotechnology from the University of Galway and a PhD in Neuroscience from the University of Bristol, and he worked as a postdoctoral researcher at the University of Nottingham. His research focuses on the affective and cognitive dimensions of pain, stress-pain interactions, and neuroinflammatory processes, with an emphasis on the endogenous cannabinoid system. He is Past-President of the International Cannabinoid Research Society (ICRS) and of the Irish Pain Society. He has been a member of the Presidential Task Forces for Cannabis, Cannabinoids, and Chronic Pain of both the International Association for the Study of Pain (IASP) and the European Pain Federation (EFIC), and leader of the Basic Science Work Package for the IASP Task Force. He is a member of the EFIC Working Groups for Translational Pain Research and Pain Research Strategy, the IASP Task Force for Use of Animals in Pain Research, a member of the Scientific Programme Committees for the IASP 2026 and 2024 World Pain Congresses, NeuPSIG 2025, EFIC 2022, and a member of EFIC Council. Professor Finn is a member of the Editorial Boards of multiple international scientific journals, including Pain, Journal of Psychopharmacology, Frontiers in Neuropharmacology, Frontiers in Pain Research, and the Scandinavian Journal of Pain. He has published over 200 peer-reviewed journal papers and book chapters and frequently lectures at international conferences.
$i++ ?>Dr. Michelle Roche
Associate Professor in Physiology and Co-Director
Centre for Pain Research at the University of Galway
Dr Roche is an Associate Professor in Physiology and Co-Director of the Centre for Pain Research at the University of Galway, Ireland. Her research interests focus on enhancing understanding of the neurobiology and pathophysiology underlying pain, mood disorders, autism and their interactions. She has a particular interest sex differences and the role of the neuro-immune, endocannabinoid and opioid systems. Her research Her research has resulted in over 80 research manuscripts, reviews and book chapters and supported by EU, national and industry funding. Dr Roche is currently European Pain Federation EFIC council member and immediate past-president of the Irish Pain Society (2023-2025). Dr Roche has contributed to and lead on several international networks including as scientific coordinator for PAINDIFF and Enlight PainNet and as the Scientific Communications Coordinator for EU-SABV Cost Action. She is an Editorial Board member of several international scientific journals including Frontiers in Pain Research and Neuropharmacology.
$i++ ?>Jeffrey S. Mogill, PhD, FCAHS, FRSC
Professor
McGill University, Montreal, Canada
Jeffrey S. Mogil is the E.P. Taylor Professor of Pain Studies and a Distinguished James McGill Professor at McGill University, where he formerly directed the Alan Edwards Centre for Research on Pain. He earned a B.Sc. (Honours) in Psychology from the University of Toronto (1988) and a Ph.D. in Neuroscience from UCLA (1993), completed a postdoctoral fellowship in Portland, Oregon (1993–1996), joined the University of Illinois at Urbana–Champaign faculty, and moved to McGill in 2001. A Fellow of the Royal Society of Canada and the Canadian Academy of Health Sciences, Dr. Mogil is renowned for seminal work in pain genetics, sex differences in pain and analgesia, and algesiometric testing in mice; he authored landmark reviews and edited the first textbook in the field, The Genetics of Pain (IASP Press, 2004). He has published 270+ papers and chapters since 1992, delivered nearly 400 invited lectures, holds an h-index of 100 (Google Scholar), and his work has been cited 40,000+ times; a 2022 Stanford analysis ranked him 7th in Anesthesiology and 210th in Neuroscience worldwide. His research has been supported by NIH, CIHR, NSERC, and leading foundations; current support includes a CIHR Foundation Grant, NSERC Discovery Grant, CIHR Sex and Gender Science Chair, and LAEF. Honors include major awards from IASP, CPS, and APS. He has served as Section Editor (Neurobiology) for Pain, chaired the 13th World Congress on Pain Scientific Planning Committee, sat on the IASP Council, and founded the North American Pain School.
$i++ ?>Kevin A. Keay
Professor of Neuroscience and Chief Anatomist
Chief Anatomist in the School of Medical Sciences at the University of Sydney
Kevin A. Keay is a Professor of Neuroscience and Chief Anatomist in the School of Medical Sciences at the University of Sydney. He is known for his research on the neural circuits that underpin emotional coping behaviours, particularly those involved in the transition from acute injury to chronic pain. His work has contributed to understanding of how midbrain, hypothalamic, and cortical networks interact to regulate active and passive responses to pain and stress. Using a multidisciplinary approach that integrates behavioural, physiological, neuroanatomical, and molecular methods, Professor Keay has contributed to improving the translational relevance of preclinical pain models. He has authored more than 125 peer-reviewed, and widely cited publications, supported by continuous competitive research funding. Professor Keay has supervised over 40 PhD students and is widely recognised for his commitment to mentorship, research excellence, and fostering inclusive scientific environments. He has held academic and research appointments in both Australia, United Kingdom, and the US. Through sustained international collaboration and leadership within the pain research community, he continues to advance understanding of chronic pain mechanisms and their clinical translation.
$i++ ?>Carina Stenfors
Professor
Åbo Akademi University in Drug Research
Dr Carina has a PhD in Neuropsychopharmacology from the Karolinska Institute and a Docent from Åbo Akademi University in Drug Research. Carina has 30 years of experience in drug discovery in the Pharma industry, where her focus has been on cross-discipline pain research for most of this time.
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Contains 3 Component(s)
2026 World Congress on Pain Refresher Courses
Abstract
Neuromodulation is a rapidly evolving field in pain medicine, offering a range of non-invasive and invasive interventions that target the nervous system to alleviate pain. This refresher course provides a comprehensive, evidence-informed overview of contemporary neuromodulation approaches for people living with pain, integrating mechanistic insights, clinical applications, and critical appraisal of the current evidence base.
The course will begin with an overview of non-invasive brain stimulation techniques, including transcranial magnetic and electrical stimulation, highlighting their supposed mechanisms of action, neurological effects, and potential future developments. It will then examine invasive neuromodulation approaches, such as spinal cord stimulation, dorsal root ganglion stimulation, peripheral nerve stimulation, and emerging technologies, with a focus on clinical indications, patient selection, and evolving stimulation paradigms.
A central theme of the course is the critical evaluation of evidence. Faculty will explore the strengths and limitations of the current neuromodulation literature, including challenges in trial design (e.g., blinding, placebo effects, and heterogeneity), interpretation of open-label versus sham-controlled studies, and the influence of industry involvement. Attendees will be guided in interpreting findings from systematic reviews, randomised controlled trials, and real-world data, with an emphasis on identifying bias and understanding uncertainty in evidence synthesis.
Finally, the course will address future directions in neuromodulation, including precision medicine approaches, closed-loop systems, and integration into multidisciplinary pain care pathways. By combining methodological rigor with clinical relevance, this course will equip participants with the knowledge and skills to critically engage with neuromodulation research and apply evidence-based approaches in both clinical and research settings.
Educational objectives:
By the end of this course, participants will be able to:
- Differentiate between major non-invasive and invasive neuromodulation techniques used in pain management, including their mechanisms of action and clinical indications.
- Appreciate clinical decision-making processes for neuromodulation therapies across different pain conditions.
- Critically appraise the current evidence base for neuromodulation interventions (spinal cord stimulation and non-invasive brain stimulation), with reference to key trial design challenges and methodological limitations.
- Interpret findings from systematic reviews and clinical trials in neuromodulation, identifying sources of bias, heterogeneity, and challenges in evidence synthesis.
- Discuss emerging technologies and future directions in neuromodulation.
- Apply knowledge of neuromodulation evidence to clinical or research contexts, including formulating relevant research questions or considering clinical pathways reviews.
Faculty List
Prof Markus Ploner, TU Munich
Non-invasive neuromodulation of the brain: Current state and future directions.
Lecture content:
- Overview of non-invasive neuromodulation techniques
- The effects of neuromodulation techniques on pain
- Mechanisms of neuromodulation effects on pain
- Future directions
Dr Michael Ferraro, NeuRA, UNSW
A systematic overview of current spinal cord stimulation studies: Assessing the evidence base
Lecture content:
- Overview of the SCS evidence landscape
- What the evidence says about benefits and harms
- Challenges in clinical trials of spinal cord stimulation
- Open-label versus sham-controlled trials
- Conflicts of interest in SCS research
Dr Ganesan Baranidharan, Leeds Teaching Hospitals NHS Trust / University of Leeds
Invasive neuromodulation techniques: Current state of the art, clinical trial challenges, and future directions.
Lecture content:
- Overview of established invasive neuromodulation techniques for pain management, including spinal cord stimulation, dorsal root ganglion stimulation, Multifidus muscle stimulation and peripheral nerve stimulation.
- Current clinical applications and technological advances, with emphasis on patient selection, stimulation paradigms, and outcome measures.
- Critical appraisal of the evidence base, highlighting key findings from randomised trials, registries, and real‑world data.
- Major clinical trial challenges, including issues of blinding, placebo effects, heterogeneity of patient populations, and long‑term outcome assessment.
- Future directions in invasive neuromodulation, focusing on precision medicine approaches, closed‑loop systems, improved trial design, and integration into multidisciplinary pain care.
$i++ ?>Markus Ploner
Professor
Technical University of Munich
Professor Markus Ploner investigates how the human brain generates the experience of pain. His interdisciplinary research group employs methods such as electroencephalography (EEG) and non-invasive brain stimulation to understand how the brain processes pain in healthy individuals and in people with chronic pain. The aim is to develop new approaches for the diagnosis and treatment of chronic pain. His research is guided by the principles of open, reproducible science and actively involves people with chronic pain in the research process.
Professor Ploner studied medicine in Cologne and Vienna and received his doctorate from the University of Cologne. He began his research career at the University Hospital Düsseldorf, where he also completed his specialist training in neurology. In 2007/2008, he conducted research at the University of Oxford as a Feodor Lynen Fellow of the Alexander von Humboldt Foundation. Since then, he has been working at the Department of Neurology at TUM. In 2014, he was appointed Professor of Human Pain Research, and in 2024, he became Head of the Center for Interdisciplinary Pain Medicine at the TUM University Hospital.
$i++ ?>Michael Ferraro, PhD, BSc Hons
Postdoctoral Researcher
NeuRA's Centre for Pain IMPACT
Dr Michael Ferraro (PhD, BSc Hons) is a postdoctoral researcher at NeuRA's Centre for Pain IMPACT. Michael's research is centred around the evaluation of treatments for chronic pain disorders, particularly complex regional pain syndrome and neuropathic pain. He also has research interests in clinical trial methodology, evidence synthesis, and research transparency. Michael's work has been published in leading general medical and specialty journals, and presented at premier conferences both internationally and nationally.
$i++ ?>Ganesan Baranidharan
Consultant in Anaesthesia and Pain Medicine
Anaesthesia and Pain Medicine at Leeds Teaching Hospitals NHS Trust
Dr G. Baranidharan has been a Consultant in Anaesthesia and Pain Medicine at Leeds Teaching Hospitals NHS Trust, United Kingdom, since 2006, serving as Clinical Lead from 2012 to 2026. He also holds an appointment as an Honorary Clinical Associate Professor at the University of Leeds.
A recognised leader in neuromodulation, Dr Baranidharan pioneered the development of the Leeds Neuromodulation Centre, transforming it from a small service into one of the most significant units in Europe. His research and clinical interests focus on neuropathic pain, neuromodulation, and the management of pain originating from visceral structures. He is widely published in peer‑reviewed journals and remains active in clinical research, teaching, and national service development.
Dr Baranidharan has made major contributions to the establishment of the National Neuromodulation Registry for the United Kingdom and currently chairs its Dataset Committee. In September 2025, he was elected Dean of the Faculty of Pain Medicine of the Royal College of Anaesthetists (FPM), where he also serves as an examiner.
Since 2008, he has successfully led an annual cadaveric pain procedures workshop in Leeds, recognised internationally for its educational excellence (www.paincourse.co.uk).-
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Contains 5 Component(s)
2026 World Congress on Pain Refresher Courses
Abstract:
This refresher course addresses the complex challenges of identifying and managing neuropathic pain in children and youth, a population for whom evidence-based guidelines are historically lacking. By integrating translational science with the most current multidisciplinary clinical expertise and lived experience, this session provides a "bench-to-bedside" framework for care and management of neuropathic pain in pediatric populations.
Dr. Michael Jankowski presents recent breakthroughs in glial-driven pain, specifically how Schwann cell signaling mediates mechanical hypersensitivity in neuropathic pain conditions including disorders like neurofibromatosis.
Dr. Suellen Walker introduces multimodal assessment strategies, including screening tools, quantitative sensory testing (QST), and genetic analysis, to improve neuropathic pain classification and inform management.
This refresher course features the perspective of Vina Mohabir who brings lived and living experience of neuropathic pain, situating assessment within the relationship between a young person and their care team — centring the outcomes that matter most to youth and families.
Following this collaborative foundation, Dr. Brittany Rosenbloom and Dr. Giulia Mesaroli will present psychological interventions and physical strategies tailored to specific pain phenotypes. Together, this approach aims to replace the traditional "trial and error" method with precision-based interdisciplinary care that reduces polypharmacy and optimizes functional outcomes for pediatric populations.
Educational objectives:
By the end of this course, participants will be able to:
- Understand the biological mechanisms and lived perspective of neuropathic pain.
- Evaluate assessment of neuropathic pain and evidence for pharmacological management.
- Describe the integration of psychological and physical therapy strategies into a comprehensive care plan for neuropathic pain in children and youth.
Michael Jankowski, PhD, Department of Anesthesia, Division of Pain Management , Cincinnati Children’s Hospital Medical Center
Title: Schwann Cells and Neuropathic Pain.
Lecture content:
This talk will discuss the fundamental role of peripheral nervous system glial cells in nerve injury related pain. An overview of neuropathic pain will be presented along with how Schwann cells (SCs) in particular play a role in sensory modulation. Specifically, this session will highlight recent breakthroughs in how SCs release neurotrophic factors (e.g. glial cell line-derived neurotrophic factor, GDNF) to sensitize adjacent sensory neurons leading to pain-like behaviors. This work will be presented in the context of the tumor predisposition syndrome, neurofibromatosis 1, where SCs are thought to be a major facilitator of neuropathic pain like phenomena.
Suellen Walker, MD, MSc, PhD
Title: Assessment and current evidence for management of neuropathic pain in paediatric populations.
Lecture content:
Neuropathic pain in children can be severe and persistent, difficult to recognise and manage, and clinical presentations vary with age and the underlying condition. A multimodal approach to assessment, with evidence from clinical and research methodologies, will be discussed. Attendees will gain an understanding of a step-wise approach to the recognition and management of neuropathic pain.
Clinical history and screening tools underpin recognition of possible neuropathic pain. Quantitative sensory testing (QST) can identify the degree, distribution and profile of sensory changes. Genetic analysis is diagnostic for some neuropathic conditions that present in childhood and can inform management. Current evidence for pharmacological management will be outlined, but is based on limited numbers of paediatric studies and extrapolation from evidence in adults. Patient-and parent-reported outcome measures and multidisciplinary assessment highlight pain-related disability and co-morbidities, and inform the multi/interdisciplinary management of chronic pain.
Vina Mohabir, MSc, PhD Student, Health Systems Research (Health Informatics), Institute of Health Policy, Management and Evaluation (IHPME), University of Toronto; Patient Partner and Trainee, iOUCH Pain Lab, Child Health Evaluative Sciences, SickKids Research Institute
Title: Nothing about us without us: lived experience and collaborative goal-setting in paediatric neuropathic pain
Lecture content:
This talk positions the lived and living experience of neuropathic pain as central to its assessment and management. Drawing on both research and personal experience, the session considers how clinical assessment is experienced from a young person's perspective, and where formal assessment and everyday priorities diverge. Much of this divergence is relational. The therapeutic relationship, and in particular trust and the experience of being believed, shapes what a young person is willing to disclose, and consequently what an assessment is able to capture. Collaborative goal-setting is therefore foundational rather than supplementary. Meaningful treatment depends on a purpose co-developed with young people and their families. Care that overlooks this risks focusing on what is easiest to measure rather than what matters most to young people. Such partnership shifts practice from a trial-and-error approach toward care that is responsive, compassionate, respectful, and fit for a shared purpose. Attendees will gain practical strategies to elicit and act on patient-defined goals, and a stronger rationale for recognizing lived experience as a form of knowledge that sits alongside mechanistic and clinical evidence in paediatric neuropathic pain._____________________________________________________________________________
Speaker #4. Dr. Brittany Rosenbloom
______________________________________________________________________________
Dr. Giulia Mesaroli, PT, PhD, The Hospital for Sick Children
Title: Physical strategies to manage neuropathic pain in the pediatric population
Lecture content: This presentation will first provide an overview of the theoretical foundations and key principles that underpin physical strategies for pediatric chronic pain management. Then, participants will be introduced to a range of treatment approaches, including physical activity and exercise, sensory-based treatments, and motor imagery interventions, with discussion of their proposed mechanisms of action and role in rehabilitation.
Building on this foundation, the session will explore the evidence and clinical application of these interventions in pediatric neuropathic pain populations. Attendees will gain a deeper understanding of how physical strategies can be integrated into comprehensive care plans to improve function, participation, and quality of life for children and adolescents experiencing neuropathic pain.
$i++ ?>Michael Jankowski, MD
Professor
Cincinnati Children's Hospital
Dr. Jankowski is the Theodore W. Striker, MD Chair in Anesthesia Research, a Professor and Vice Chief for Research in the Department of Anesthesia at Cincinnati Children's Hospital. His research focuses on basic mechanisms of nociception and how these mechanisms change across the lifespan with a focus on neuroimmune and non-neuronal communication.
$i++ ?>Giulia Mesalori
Physiotherapist, Researcher and Educator
The Hospital for Sick Children
Giulia Mesaroli is a physiotherapist, researcher, and educator with a focus on pediatric pain management. She works clinically as a physiotherapist in the Department of Rehabilitation Services at The Hospital for Sick Children. Her clinical and research interests include neuropathic pain, complex regional pain syndrome, and the use of digital technologies to assess and treat pediatric chronic pain within rehabilitation settings.
$i++ ?>
Vina Mohabir, MSc, PhD Student
Vina Mohabir, MSc, is a patient partner and PhD student in Health Systems Research at the Institute of Health Policy, Management and Evaluation, University of Toronto. She is a trainee in the iOUCH Pain Lab within Child Health Evaluative Sciences at SickKids Research Institute, where her work focuses on co-designing digital health tools with young people living with painful conditions alongside intersecting forms of discrimination. She brings research training together with lived and living experience of neuropathic and chronic pain to her advocacy, with a focus on what matters most to young people and their families.
$i++ ?>Suellen Walker
Professor of Paediatric Pain Medicine
UCL GOS Institute of Child Health and Great Ormond Street Hospital
Suellen Walker is Professor of Paediatric Pain Medicine, UCL GOS Institute of Child Health and Great Ormond Street Hospital, London, UK. Current activities include paediatric pain clinical practice, and she is Principal Investigator in the UCL GOS ICH Paediatric Pain Research Group. Her research interests include the long-term impact of pain experience during childhood, and paediatric neuropathic pain. (https://profiles.ucl.ac.uk/303-suellen-walker).
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Contains 5 Component(s)
2026 World Congress on Pain Refresher Courses
Abstract
This refresher course focuses on technologies used to assess normal and altered somatosensory sensitivity and pain mechanisms, as well as neurophysiological techniques for studying central nervous system manifestations of pain.
Quantitative Sensory Testing (QST) has advanced the standardisation of somatosensory assessment in pain research since the early 2000s. QST technologies provides a structured evaluation of somatosensory function across different fibre classes and sensory modalities through patient-reported responses, capturing parameters that are difficult to assess using objective neurophysiological methods. Dr. Magerl presents the development and application of these QST techniques, now widely used in patient group studies and individual diagnostics.
QST has largely been developed for assessing superficial structures, although manifestations of sensitisation in pain mechanisms associated with deeper tissues are of considerable clinical importance. Dr. Graven-Nielsen introduces the assessment of pain sensitivity, temporal summation of pain, and conditioned pain modulation relevant to deep tissues (e.g. muscle), as well as pain referral.
Resting-state electroencephalography (EEG) has emerged as a valuable tool for investigating the neural mechanisms underlying pain and chronic pain conditions. Capturing spontaneous brain activity without experimental stimulation, resting-state EEG provides insights into altered brain function, network dynamics, and potential pain biomarkers. Dr. Ploner presents the rationale for using resting-state EEG in pain research, outline common methodological approaches, summarise key findings, and discuss current challenges and future directions for its clinical and research use.
Complementing the resting-state EEG session, Dr. Mouraux introduces event-related potentials (ERPs) recorded with non-invasive EEG to characterise nociceptive processing and its modulation in healthy individuals and clinical populations. This lecture will guide participants through the methodological requirements for recording brain responses to sensory stimuli and the available stimulation modalities, including infrared laser, contact heat and cold, and mechanical pinprick stimulation. The lecture discusses interpretation of responses, highlighting key limitations and pitfalls, and concludes with emerging approaches to distinguish EEG activity linked to sustained versus transient nociceptive input.
Dr. Moayedi will cover the basic principles of structural and functional neuroimaging, focusing on magnetic resonance imaging (MRI). Specifically, the lecture will summarise key findings from MRI studies relevant to pain and related conditions. The session will highlight how neuroimaging has advanced understanding of brain pain mechanisms in health and disease. It will also provide an overview of their strengths and current limitations in research and clinical contexts.
Educational objectives
- To provide an understanding of somatosensory function and neurophysiologically informed assessment using QST.
- To introduce the assessment of pain sensitivity, temporal summation, conditioned pain modulation, and pain referral in deep tissues using QST-based approaches.
- To develop an understanding of the potential of resting-state EEG for investigating pain mechanisms, as well as its key methodological and interpretative challenges.
- To understand the potential and limitations of event-related brain potentials in human pain research and to gain knowledge of their implementation and analytical tools required.
- To understand the principles, applications, strengths, and limitations of structural and functional MRI in pain research.
Faculty List
Walter Magerl (Department of Neurophysiology, Universität Heidelberg, Heidelberg, Germany.)
Quantitative Sensory Testing: Methods and Interpretations.
Thomas Graven-Nielsen (Center for Neuroplasticity and Pain (CNAP), Aalborg University, Aalborg, Denmark)
Deep-tissue Quantitative Sensory Testing: Methods and Interpretations
Markus Ploner (Center for Interdisciplinary Pain Medicine, Technical University of Munich, Munich, Germany)
Resting-state Electroencephalography in Pain Research: Methods and Interpretations.
André Mouraux (Institute of Neuroscience (IoNS), UCLouvain, Brussels, Belgium)
Evoked Brain Potentials in Pain Research: Methods and Interpretations.
Massieh Moayedi (Centre for Multimodal Sensorimotor and Pain Research, University of Toronto, Toronto, Canada)
Pain NeuroImaging with MRI: Methods and Interpretations.
$i++ ?>Massieh Moayedi, PhD
Research Chair
University of Toronto Centre for the Study of Pain
Massieh Moayedi is a Canada Research Chair in Pain Neuroimaging, a University of Toronto Centre for the Study of Pain scientist, and co-director of the Multimodal Sensorimotor and Pain Research. Moayedi received his PhD under the supervision of Karen Davis and completed a postdoctoral fellowship at University College London under the supervision of Giandomenico Iannetti. He is Secretary of the Canadian pain Society, and Councilor of the International Association for the Study of Pain. Moayedi's interest in pain research is borne out of personal lived experience with pain. His work uses brain imaging and behavioral paradigms to delineate the mechanisms of acute and chronic pain, with a goal of identifying novel therapeutic targets. He has an extensive collaborative network of clinicians and scientists with expertise to answer complex questions in pain physiology.
$i++ ?>Markus Ploner
Professor
Technical University of Munich
Professor Markus Ploner investigates how the human brain generates the experience of pain. His interdisciplinary research group employs methods such as electroencephalography (EEG) and non-invasive brain stimulation to understand how the brain processes pain in healthy individuals and in people with chronic pain. The aim is to develop new approaches for the diagnosis and treatment of chronic pain. His research is guided by the principles of open, reproducible science and actively involves people with chronic pain in the research process.
Professor Ploner studied medicine in Cologne and Vienna and received his doctorate from the University of Cologne. He began his research career at the University Hospital Düsseldorf, where he also completed his specialist training in neurology. In 2007/2008, he conducted research at the University of Oxford as a Feodor Lynen Fellow of the Alexander von Humboldt Foundation. Since then, he has been working at the Department of Neurology at TUM. In 2014, he was appointed Professor of Human Pain Research, and in 2024, he became Head of the Center for Interdisciplinary Pain Medicine at the TUM University Hospital.
$i++ ?>Thomas Graven-Nielsen, PhD
Director at
Center for Neuroplasticity and Pain, Aalborg University.
Thomas Graven-Nielsen acquired his PhD within Biomedical Science and Engineering in 1997 (Aalborg University, Denmark). In 2006 he obtained a Doctoral degree in Medical Science (DMSc, Copenhagen University). He is Director at Center for Neuroplasticity and Pain (CNAP), Aalborg University, Denmark (since 2015), and Full Professor in Pain Neuroscience since 2008. The Danish National Research Foundation inaugurated CNAP. He is also Councillor in the International Association for the Study of Pain.
The research focuses on translational studies of pain bridging the gap between basic animal findings and clinical manifestations of pain. The scope is to identify and modulate key features of human pain neuroplasticity leading to prevention of maladaptive neuroplasticity and promote advantageous neuroplasticity. The core areas are musculoskeletal pain, referred pain, localised and widespread deep-tissue hyperalgesia, pain modulatory mechanisms, pharmacological screening, and electrophysiological techniques to assess pain physiology and neuroplasticity. Novel pain models, bio-markers, assessment and neuro-modulatory technologies are key biomedical tools for the translational studies.
A core research philosophy in his work is that pain research by nature is multidisciplinary, hence interdisciplinary and intersectorial collaboration is a key concept, as is collaboration with excellent researchers and students. Thomas has published 385+ peer-reviewed scientific papers (H-index: 78, approx. 20.000 citations) and received several awards, most notably the Knight of the Order of Dannebrog (2020). He reviews papers on a regular basis for high ranked journals, has presented as keynote speaker at several international conferences, and organised scientific workshops and symposia at international meetings. Multiple national and international collaborations on translational pain research have been established. Moreover, advocacy for pain research has been a cornerstone activity via dedicated involvement.
$i++ ?>André Mouraux MD, PhD
Full Professor
UCLouvain Institute of Neurosciences (IoNS)
André Mouraux (MD, PhD) is Full Professor at the UCLouvain Institute of Neurosciences (IoNS). As a neuroscientist trained as a clinical neurologist, his research focuses on the cerebral mechanisms underlying nociception and pain perception in humans, using electroencephalography (EEG) – including intracerebral EEG – combined with techniques to selectively activate distinct classes of nociceptive afferents. A central theme of his work is understanding the changes in nociceptive processing induced by inflammation, injury, or sustained nociceptive input that drive peripheral and central sensitization, and may contribute to the transition from acute to chronic pain. He has contributed to the development of pharmacodynamic biomarkers of nociceptive processing within large European collaborative projects, including IMI2-PAINCARE and H2020-QSPainRelief, and is currently involved in MSCA-FRESCO4NoPain, which explores non-invasive brain stimulation as a means to modulate pain.
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- Member - $109
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- Trainee - $109
- Life Member - $109
- Life Honorary - $109
- Honorary - $109
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Contains 4 Component(s)
2026 World Congress on Pain Refresher Courses
Abstract:
Chronic pain is complex and effective treatment is a formidable challenge for both patients and clinicians. Promoting successful self-management and returning to valued life activities are often key goals of treatment, but facilitating this trajectory in patients with long-standing pain can be difficult. Indeed, pain is inherently a psychosocial experience, yet many clinicians feel under-equipped to integrate relevant (and necessary) psychological principles and behavioural components into their care.
In this course, you will hear from field-leaders whose research sits at the forefront of psychologically informed care. Targeting both clinicians and researchers, this course aims to provide the latest knowledge across a spectrum of psychologically informed interventions, paired with real-world strategies to embed these principles into clinical practice.
The overall goal is to upskill attendees in the use of psychologically informed care for chronic pain by improving the understanding and application of relevant psychological principles in communication and treatment.
Educational Objectives:
By the end of this course, participants will be able to:
- To understand the principles of cognitive functional therapy as a person-centred behavioral approach, explore its clinical application for people presenting with chronic low back pain, and the CFT training pathway available for clinicians.
- To understand the emerging theory of ‘mindsets’ in health, including novel mindset interventions and how they can be applied in clinical practice
- To appreciate the importance of patient validation and come away with new strategies that can be implemented in the clinical setting with people who have chronic pain.
- To enable participants to more adequately identify targets for treatment that enable more successful and vital living with the ongoing experience of chronic pain, including the direct application of interventions to augment willingness to experience chronic pain in the service of engagement in personally meaningful action, and present-focused awareness to enable such actions to occur.
Faculty List
JP Caneiro, BScPhysio, MSportPhysio, PhD, FACP – Specialist Physiotherapist; Adjunct Senior Clinical Research Fellow, School of Allied Health, Faculty of Health Sciences, Curtin University, Western Australia; co-Director, Evoolve Pain Care Academy, Western Australia
Cognitive Functional Therapy Unpacked: Principles, Practice, and Training Pathway.
Lecture content:
Chronic disabling low back pain remains a major clinical challenge, with biomedical approaches often failing to address its multidimensional nature. Despite endorsement of biopsychosocial models, physiotherapists frequently report limited confidence in managing psychosocial contributors to pain. Cognitive Functional Therapy (CFT), a person-centred behavioural approach, has demonstrated superior and sustained outcomes in pain, disability, and self-efficacy compared to usual care, as evidenced by the RESTORE trial published in The Lancet. Supported by structured, competency-based training, CFT enables clinicians to develop the skills required for effective, individualized care. This presentation explores the principles, clinical application, and training pathway of CFT, alongside initiatives to improve global access to high-quality clinician education.
Lauren Heathcote, PhD, Reader in Health Psychology, Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, UK.
Mindsets Matter: Leveraging Patient Beliefs to Improve Pain and Health
Lecture content:
Beliefs about the body, illness, and recovery are not just reflections of health; they actively shape it. Emerging research on mindsets – core beliefs or assumptions about domains like the body, illness, or pain – offers a powerful framework for understanding how these beliefs influence pain and health outcomes. In this talk, Lauren will introduce contemporary theory and evidence on mindsets, highlighting how patients’ beliefs about their bodies and illnesses can alter physiological, behavioural, and psychological processes relevant to pain. She will focus on specific mindsets that appear particularly influential in chronic pain and illness, including beliefs about bodily capacity, symptom meaning, and recovery potential. Finally, she will present novel, scalable mindset interventions that are demonstrating promising effects on pain, functioning, and wellbeing across clinical populations. The session will conclude with practical guidance for integrating mindset-informed approaches into clinical care to enhance patient outcomes.
Sarah Wallwork, PhD, B.Physio(Hons) – Senior Research Fellow, IIMPACT in Health, Robinson Research Institute, Adelaide University, Australia
“I Hear You, I See You, I Believe You”: The power of patient validation
Abstract: People with chronic pain regularly report pain dismissal, disbelief, and invalidation from healthcare professionals, having a negative impact on their health and mental and emotional wellbeing. In this presentation, Sarah will talk about how clinicians, including those from non-psychological disciplines, can intentionally use validating communication to improve outcomes for their patients. She will draw on the biosocial theory of emotion regulation to discuss how validating communication can increase therapeutic rapport, treatment adherence, and overall health outcomes while invalidating communication can lead to mistrust, emotion dysregulation, and poor mental health. Specific strategies and examples will be provided.
Kevin Vowles, PhD - Professor of Clinical Psychology, School of Psychology, Queen’s University Belfast and Belfast Centre for Pain Rehabilitation, Belfast Health and Social Care Trust
Willingness, Awareness, and Meaningful Action in Response to Chronic Pain.
Lecture content: Chronic pain is a profound source of human suffering and disability. Robust evidence shows that when individuals with chronic pain let go of the struggle for pain control, cultivate openness and curiosity to present-moment experiences, and commit to values-driven actions, they experience less suffering and improved functioning – even while pain persists. These processes - acceptance/willingness, present-focused awareness, and values-based action - are the cornerstones of Acceptance and Commitment Therapy (ACT), a well-established behavioral intervention for chronic pain. This presentation will outline the ACT model, including its intervention goals, therapeutic methods, and key clinical considerations. A central tenet of ACT is that a rich, meaningful, and fulfilling life is possible without relentless pursuit of pain reduction, relief, or management. This perspective offers both hope and liberation not only for those living with chronic pain, but also for treatment providers.
$i++ ?>J.P. Caneiro
Specialist Physiotherapist & Adjunct Senior Clinical Researcher
Curtin University
Dr J.P. Caneiro is a Specialist Physiotherapist who combines clinical practice with his role as Adjunct Senior Clinical Researcher at Curtin University, and co-Director and Educator of Evoolve Pain care Academy, a social enterprise promoting equitable access to evidence-based musculoskeletal pain care and clinician training worldwide. Dr Caneiro is an integral part of the team that has developed a novel management approach for people disabling low back pain – called ‘Cognitive Functional Therapy’. This treatment has demonstrated efficacy in numerous clinical trials, including a recent landmark trial published in The Lancet in which Dr Caneiro was one of the lead trainers. With over 50 peer-reviewed publications and international conference presentations, he is an emerging leader on the field of chronic pain, particularly in the management of back pain and osteoarthritis. Dr Caneiro has taught on the Masters of Physiotherapy program at Curtin University, and he consults at bodylogic.physio where he reviews patients with complex musculoskeletal pain presentations. Dr Caneiro is dedicated to bridge the evidence-to-practice gap by mentoring clinicians to deliver high-quality, person-centred care.
$i++ ?>Lauren Heathcote
Associate Professor)
Health Psychology at the Institute of Psychiatry, Psychology & Neuroscience at King’s College London
Dr Lauren Heathcote is a Reader (Associate Professor) in Health Psychology at the Institute of Psychiatry, Psychology & Neuroscience at King’s College London. She received her PhD in Experimental Psychology from the University of Oxford and completed a five-year Postdoctoral Fellowship in >span class="NormalTextRun SCXW179073375 BCX0">Pain Medicine division at Stanford University School of Medicine. She was the 2022 recipient of the prestigious Ulf Lindblom Young Investigator Prize for Clinical Science from the International Association for the Study of Pain as well as the 2022 Hiroomi Kawano New Investigator Award from the International Psycho-Oncology Society, both in recognition for her early and distinguished contributions to pain and psycho-oncology research.
>span class="NormalTextRun SCXW179073375 BCX0">identify mind-body mechanisms of physical and mental health and to harness these using innovative behavioural medicine approaches to improve the lives of young people and adults living with and beyond chronic illness.
$i++ ?>Sarah Wallwork
Senior Research Fellow
IIMPACT in Health and at the Robinson Research Institute at Adelaide University
Dr. Sarah Wallwork is a Senior Research Fellow and physiotherapist within IIMPACT in Health and at the Robinson Research Institute at Adelaide University. She leads a program of research that targets childhood to reduce the prevalence and burden of chronic pain in young people and adults. Her work explores the ecology in which a child is situated, including interconnected social, cultural and societal contexts, and how that may shape a child’s resilience against chronic pain. She has been awarded >$4.3m in funding, has published >45 peer-reviewed articles, has been invited speaker to 26 national/international conferences/seminars, and has been recipient of multiple national and international competitive scholarships. In 2021, she was named Field Leader in The Australian Research Magazine’s top researchers from 250 fields of research.
$i++ ?>Kevin Vowles, PhD
Professor
Clinical Psychology at Queen’s University Belfast
Kevin E. Vowles is a clinical psychologist and researcher specializing in the psychological and behavioral processes that influence adaptation to chronic pain. His work examines how acceptance, present-moment awareness, and values-based action can support individuals in engaging with meaningful activities, even in the context of persisting pain. As a Professor of Clinical Psychology at Queen’s University Belfast and clinician at the Belfast Centre for Pain Rehabilitation (UK NHS), Kevin has contributed to the development and evaluation of Acceptance and Commitment Therapy (ACT) as an evidence-based intervention for chronic pain. This work, which has been cited by the UK’s National Institute for Health and Care Excellence (NICE) and is recognized for its empirical support by the American Psychological Association’s Division of Clinical Psychology, highlights a critical insight: having a full and meaningful life is not dependent on reducing pain. With over 150 peer-reviewed publications, Kevin’s research has informed clinical guidelines and academic discourse on chronic pain and its treatment goals. His work aims to bridge the gap between scientific rigor and clinical utility, supporting individuals in re-engaging with valued life activities with ongoing chronic pain. Alongside research, Kevin is involved in education, training, and community work collaborating with clinicians and researchers worldwide to integrate these principles into practice. His ultimate goal is to empower people to live fully, even when pain persists.
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